3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-[(1E)-({[3-(trifluoromethyl)phenyl]methoxy}amino)methylidene]thiourea CAS 477873-19-1
| CAS No. | 477873-19-1 |
| Molecular Formula | C16H11ClF6N4OS |
| Molecular Weight | 456.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 456.79 g/mol gives 3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-[(1E)-({[3-(trifluoromethyl)phenyl]methoxy}amino)methylidene]thiourea distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-[(1E)-({[3-(trifluoromethyl)phenyl]methoxy}amino)methylidene]thiourea (CAS 477873-19-1), molecular formula C16H11ClF6N4OS and molecular weight 456.79 g/mol, is a CATO reference standard with documented purity and traceability.
3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-[(1E)-({[3-(trifluoromethyl)phenyl]methoxy}amino)methylidene]thiourea (C16H11ClF6N4OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-[(1E)-({[3-(trifluoromethyl)phenyl]methoxy}amino)methylidene]thiourea under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H11ClF6N4OS |
| Molecular Weight | 456.79 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(phenylcarbamoyl)amino]-4,5-dihydro-1,2-oxazole-3-carboxamide (CAS 338399-32-9)
- {5-chloro-1-methyl-3-[(phenylsulfanyl)methyl]-1H-pyrazol-4-yl}methyl N-(3,4-dichlorophenyl)carbamate (CAS 400087-20-9)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(3-methoxybenzyl)-1-methyl-1H-imidazole-5-carboxamide (CAS 339278-17-0)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5-[(E)-2-[(4-fluorophenyl)amino]ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338413-05-1)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)-N-(3,5-dimethylphenyl)benzenesulfonamide (CAS 338775-29-4)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}-N-(2,3-dimethylphenyl)benzene-1-sulfonamide (CAS 338775-36-3)
- 2-Chloro-N'-(2-(4-methoxyphenyl)imidazo[1,2-a]pyridine-6-carbonyl)benzenesulfonohydrazide (CAS 866137-85-1)
- 3-(3-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1-tosyl-1H-pyrazole (CAS 477712-64-4)
Recommended Standards
- 3-(2-Bromophenyl)-5-((4-chlorobenzyl)thio)-4-phenyl-4H-1,2,4-triazole (CAS 443740-40-7)
- Cholesteryl isoamyl ether (CAS 74996-30-8)
- 3-(2-Bromophenyl)-5-((2-chlorobenzyl)thio)-4-phenyl-4H-1,2,4-triazole (CAS 443740-39-4)
- ((Propane-2,2-diylbis(4,1-phenylene))bis(oxy))bis(tert-butyldimethylsilane) (CAS 111983-38-1)
- (Z)-4-Hydroxy-4-(pyridin-2-yl)but-3-en-2-one (CAS 1031694-63-9)
- 1-(4-Bromo-2-fluorophenyl)-5-(1h-pyrrol-1-yl)-1h-pyrazole-4-carboxylic acid (CAS 1224155-10-5)
- Diethyl 4-amino-1H-imidazole-2,5-dicarboxylate (CAS 83566-38-5)
- 5-(Phenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide (CAS 3368-13-6)
- 4-(3-(tert-butylamino)-2-hydroxypropoxy)-1H-indole-2-carbonitrile (CAS 69906-85-0)
- WX390 Impurity 4 (CAS CATO-C4X-34314)
- (Z)-1-(4-(1H-imidazol-1-yl)phenyl)ethan-1-one oxime (CAS 146139-83-5)
- 1,1'-(1,4-Phenylene)diurea (CAS 1205-90-9)
- 2-Azido-N-(4-bromo-2-fluorophenyl)acetamide (CAS 1249127-92-1)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
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