[4-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)phenyl]methanol CAS 338409-36-2
| CAS No. | 338409-36-2 |
| Molecular Formula | C19H21ClF3N3O2 |
| Molecular Weight | 415.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including [4-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)phenyl]methanol.
CATO supplies [4-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)phenyl]methanol (CAS 338409-36-2), a certified reference material (molecular formula C19H21ClF3N3O2, MW 415.84 g/mol) for analytical method development and quality control.
Based on its molecular formula C19H21ClF3N3O2, [4-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)phenyl]methanol contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 415.84 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H21ClF3N3O2 |
| Molecular Weight | 415.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
- N-(3-((5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)(hydroxy)methyl)-2,4-difluorophenyl)propane-1-sulfonamide (CAS 1021854-28-3)
- (3-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethoxy)phenyl)methanol (CAS 338409-27-1)
- 3-chloro-5-[4-({[4-methyl-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl]thio}methyl)phenyl]isothiazole-4-carbonitrile (CAS 662138-29-6)
- 5-Chloro-1-(2-phenoxyethyl)-3-phenyl-2-(trifluoromethyl)-1H-indole (CAS 338966-38-4)
- 3-(2-Chloro-6-fluorophenyl)-5-methyl-4-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]-1,2-oxazole (CAS 287176-94-7)
- 2-(2-Chloro-5-(phenylsulfonyl)benzamido)benzoic acid (CAS 724440-27-1)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(p-tolyl)-1H-pyrrole-2-sulfonamide (CAS 321433-64-1)
- 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(phenylsulfanyl)pyrrolidine-2,5-dione (CAS 338772-49-9)
Recommended Standards
- 2-(2-Chloropyridin-3-yl)-5,6-dimethyl-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-1,3-benzodiazole (CAS 339101-23-4)
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- 5-((4-Chlorophenyl)thio)-N-(3-(trifluoromethyl)phenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 303151-35-1)
- 5-Methyl-2-oxotetrahydrofuran-3-carbonitrile (CAS 76263-39-3)
- Ethyl 2-methyl-6-oxo-4-{3-[3-(trifluoromethyl)phenoxy]phenyl}-1,4,5,6-tetrahydropyridine-3-carboxylate (CAS 294853-80-8)
- 1-(2-Chlorobenzyl)-1H-pyrazol-4-ol (CAS 1592296-18-8)
- 4-(Acryloyloxy)butyl 3-oxobutanoate (CAS 13025-07-5)
- 1-(5-Fluoro-2-methylpyridin-3-yl)ethanone (CAS 1256785-71-3)
- 4-Chloroethcathinone HCl (CAS 22198-75-0)
- (3R,4S)-1-methyl-4-(3-phenylpropyl)pyrrolidin-3-amine (CAS 1951371-73-5)
- Ethyl 2-amino-4-(4-chlorophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate (CAS 107752-88-5)
- 7-Bromo-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxylic acid (CAS 59820-91-6)
- 1-(3-Chlorophenyl)-N-(2-methoxyethyl)propan-1-amine (CAS 1019604-09-1)
- Rac1 Inhibitor F56, control peptide (CAS 1315378-77-8)
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