2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}-N-(4-chlorophenyl)-2-oxoacetamide CAS 338770-20-0
| CAS No. | 338770-20-0 |
| Molecular Formula | C22H12Cl2F3N3O2 |
| Molecular Weight | 478.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}-N-(4-chlorophenyl)-2-oxoacetamide (CAS 338770-20-0), a certified reference material (molecular formula C22H12Cl2F3N3O2, MW 478.25 g/mol) for analytical method development and quality control.
2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}-N-(4-chlorophenyl)-2-oxoacetamide (C22H12Cl2F3N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}-N-(4-chlorophenyl)-2-oxoacetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H12Cl2F3N3O2 |
| Molecular Weight | 478.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
- 4-Chloro-N-(2-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)ethyl)benzenesulfonamide (CAS 547733-50-6)
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- N-(4-Chloro-2-methoxy-5-methylphenyl)-2-((3-ethyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 578759-27-0)
- 7-Chloro-N-(4-isopropylphenyl)-3-(phenylsulfonyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-amine (CAS 893787-13-8)
- (2E)-1-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-phenyl-3-(thiophen-2-yl)prop-2-en-1-one (CAS 478079-01-5)
- 4-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-N-(4-methoxyphenyl)-1,3-thiazol-2-amine (CAS 1024375-85-6)
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Recommended Standards
- Bis(perfluorophenyl) adipate (CAS 83701-40-0)
- Platinum,dichloro(1,2-diphenyl)-1,2-ethanediamine-N,N'-,[SP-4-2-[R-(R*,R*)]] (CAS 80317-01-7)
- (3,4-Diaminophenyl)-phenylmethanone,platinum(2+),dichloride (CAS 72596-00-0)
- Cefotaxime Bromoacetyl analog (CAS 83305-12-8)
- 4-(Thiazol-2-yl)morpholine (CAS 21429-06-1)
- 1-(4-Chloro-2-fluorophenyl)piperazine (CAS 515160-75-5)
- 6-Benzylpyridin-3-ol (CAS 101192-76-1)
- (5E)-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-5-[(4-chlorophenyl)methylidene]-1,3-diazinane-2,4,6-trione (CAS 306978-09-6)
- N-(3-Cyano-4-methyl-5-phenyl-1H-pyrrol-2-yl)acetamide (CAS 61404-77-1)
- D-Carnitine (CAS 541-14-0)
- 2,5-Dichloro-3-iodothiophene (CAS 43225-59-8)
- 4-Pentynamide, N-(2-aminoethyl)- (CAS 1099604-73-5)
- Methyl 3-cyclohexyl-2-(2-hydroxyphenyl)-1H-indole-6-carboxylate (CAS 863578-50-1)
- Tau Peptide (298-312) trifluoroacetate salt (CAS 330456-47-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com