3-Chloro-2-(thiophene-2-carbonyl)-5-(trifluoromethyl)pyridine CAS 338953-29-0
| CAS No. | 338953-29-0 |
| Molecular Formula | C11H5ClF3NOS |
| Molecular Weight | 291.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chloro-2-(thiophene-2-carbonyl)-5-(trifluoromethyl)pyridine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Chloro-2-(thiophene-2-carbonyl)-5-(trifluoromethyl)pyridine (CAS 338953-29-0), molecular formula C11H5ClF3NOS and molecular weight 291.68 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C11H5ClF3NOS, 3-Chloro-2-(thiophene-2-carbonyl)-5-(trifluoromethyl)pyridine contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 291.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-2-(thiophene-2-carbonyl)-5-(trifluoromethyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H5ClF3NOS |
| Molecular Weight | 291.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pyrimidine-2-thiol (CAS 1007166-51-9)
- 6-Chloro-2-(4,4-difluoropiperidin-1-yl)-4-methyl-3-nitropyridine (CAS 1253378-61-8)
- 4-(3-Chloro-5-trifluoromethyl-pyridin-2-yl)-pyrimidine-2-thiol (CAS 1311278-19-9)
- 4-Chloro-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbaldehyde (CAS 499796-75-7)
- 5-Chloro-7-(2,4-difluorophenyl)quinolin-8-ol (CAS 648896-48-4)
- 5-Chloro-7-(3,5-difluorophenyl)quinolin-8-ol (CAS 648896-47-3)
- 7-Chloro-N-(2,4-difluorophenyl)quinazolin-4-amine (CAS 477856-24-9)
- 7-Chloro-N-(2,6-difluorophenyl)quinazolin-4-amine (CAS 477856-36-3)
Recommended Standards
- 2-(4-(Trifluoromethyl)phenyl)thiazole-4-carbonyl chloride (CAS 857284-28-7)
- N-[(Chloro(phenoxy)phosphoryl)]-L-Alanine Ethyl Ester (CAS 245078-14-2)
- 2-[4-(2H-Tetrazol-5-yl)phenoxy]-5-chloro-3-fluoropyridine (CAS 1799681-96-1)
- 7-Chloro-N-(3,5-difluorophenyl)quinazolin-4-amine (CAS 477860-67-6)
- Methyl (3S)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-phenylpropanoate (CAS 1426822-90-3)
- 5,6,7,8-Tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carbaldehyde (CAS 1159530-92-3)
- (3,5-Dimethylbenzo[b]thiophen-2-yl)boronic acid (CAS 912331-80-7)
- (1-Methyl-5-phenoxy-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl acetate (CAS 956705-46-7)
- N-Methyl-1-(3-phenyl-1H-pyrazol-4-yl)methanamine (CAS 1007521-06-3)
- 2-Chloro-1-(pyridin-3-yl)ethan-1-one (CAS 55484-11-2)
- 1-Chloro-2-methyl-4-propoxybenzene (CAS 1509948-97-3)
- 5-(3-(Trifluoromethyl)phenyl)-1,2,4-oxadiazol-3-amine (CAS 462659-89-8)
- 6-Bromo-[2,3'-bipyridine]-5'-carboxamide (CAS 1346687-05-5)
- Semaglutide impurity 68 (CAS CATO-C4X-222668)
Why CATO?
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