4-Chloro-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbaldehyde CAS 499796-75-7
| CAS No. | 499796-75-7 |
| Molecular Formula | C11H5ClF3NOS |
| Molecular Weight | 291.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Chloro-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbaldehyde is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Chloro-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbaldehyde (CAS 499796-75-7) is a high-purity analytical reference standard with the molecular formula C11H5ClF3NOS and a molecular weight of 291.68 g/mol.
4-Chloro-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbaldehyde (C11H5ClF3NOS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbaldehyde under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H5ClF3NOS |
| Molecular Weight | 291.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pyrimidine-2-thiol (CAS 1007166-51-9)
- 6-Chloro-2-(4,4-difluoropiperidin-1-yl)-4-methyl-3-nitropyridine (CAS 1253378-61-8)
- 4-(3-Chloro-5-trifluoromethyl-pyridin-2-yl)-pyrimidine-2-thiol (CAS 1311278-19-9)
- 3-Chloro-2-(thiophene-2-carbonyl)-5-(trifluoromethyl)pyridine (CAS 338953-29-0)
- 5-Chloro-7-(2,4-difluorophenyl)quinolin-8-ol (CAS 648896-48-4)
- 5-Chloro-7-(3,5-difluorophenyl)quinolin-8-ol (CAS 648896-47-3)
- 7-Chloro-N-(2,4-difluorophenyl)quinazolin-4-amine (CAS 477856-24-9)
- 7-Chloro-N-(2,6-difluorophenyl)quinazolin-4-amine (CAS 477856-36-3)
Recommended Standards
- 2-(4-(Trifluoromethyl)phenyl)thiazole-4-carbonyl chloride (CAS 857284-28-7)
- 7-Chloro-N-(3,5-difluorophenyl)quinazolin-4-amine (CAS 477860-67-6)
- N-[(Chloro(phenoxy)phosphoryl)]-L-Alanine Ethyl Ester (CAS 245078-14-2)
- But-2-en-1-yl (3-chloro-4-(difluoromethoxy)phenyl)carbamate (CAS 88714-94-7)
- 3-[(2-fluorophenyl)methoxy]-4-methoxybenzaldehyde (CAS 384857-20-9)
- Ethyl Methylpiperidine-2-carboxylate (CAS 30727-18-5)
- 4-(2,4-Dimethylphenyl)-4H-benzo[b][1,4]thiazine-2-carbonitrile 1,1-dioxide (CAS 1189952-19-9)
- N-Phenyl-4-(5-phenylthiophen-2-yl)aniline (CAS 1085434-10-1)
- N-(4-Bromo-3-(trifluoromethyl)phenyl)hydrazinecarbothioamide (CAS 1303993-77-2)
- 1-(2-bromophenyl)butan-2-one (CAS 1179882-16-6)
- 3'-Methoxy-6-methyl-[1,1'-biphenyl]-3-amine (CAS 1176550-49-4)
- Tert-butyl ((1-methyl-1H-tetrazol-5-yl)methyl)carbamate (CAS 1856485-88-5)
- 3,3-Dimethyl-1,4-dihydroquinoxalin-2-one (CAS 80636-30-2)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
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