5-Chloro-7-(2,4-difluorophenyl)quinolin-8-ol CAS 648896-48-4
| CAS No. | 648896-48-4 |
| Molecular Formula | C15H8ClF2NO |
| Molecular Weight | 291.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-7-(2,4-difluorophenyl)quinolin-8-ol.
5-Chloro-7-(2,4-difluorophenyl)quinolin-8-ol (CAS 648896-48-4), molecular formula C15H8ClF2NO and molecular weight 291.68 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C15H8ClF2NO, 5-Chloro-7-(2,4-difluorophenyl)quinolin-8-ol contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 291.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Chloro-7-(2,4-difluorophenyl)quinolin-8-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H8ClF2NO |
| Molecular Weight | 291.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pyrimidine-2-thiol (CAS 1007166-51-9)
- 6-Chloro-2-(4,4-difluoropiperidin-1-yl)-4-methyl-3-nitropyridine (CAS 1253378-61-8)
- 4-(3-Chloro-5-trifluoromethyl-pyridin-2-yl)-pyrimidine-2-thiol (CAS 1311278-19-9)
- 3-Chloro-2-(thiophene-2-carbonyl)-5-(trifluoromethyl)pyridine (CAS 338953-29-0)
- 4-Chloro-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbaldehyde (CAS 499796-75-7)
- 5-Chloro-7-(3,5-difluorophenyl)quinolin-8-ol (CAS 648896-47-3)
- 7-Chloro-N-(2,4-difluorophenyl)quinazolin-4-amine (CAS 477856-24-9)
- 7-Chloro-N-(2,6-difluorophenyl)quinazolin-4-amine (CAS 477856-36-3)
Recommended Standards
- 2-(4-(Trifluoromethyl)phenyl)thiazole-4-carbonyl chloride (CAS 857284-28-7)
- 7-Chloro-N-(3,5-difluorophenyl)quinazolin-4-amine (CAS 477860-67-6)
- But-2-en-1-yl (3-chloro-4-(difluoromethoxy)phenyl)carbamate (CAS 88714-94-7)
- Roflumilast Impurity 49 (CAS CATO-C4X-108449)
- 2-Fluoro-4-methoxy-1-phenylbenzene (CAS 634192-51-1)
- Pyrimidin-2-ylcyanamide (CAS 4425-54-1)
- N-(3,5-Dimethylphenyl)-N-(methylsulfonyl)alanine (CAS 1008265-17-5)
- 5-Fluorobicyclo[3.2.2]Nonan-1-amine hydrochloride (CAS 2108852-89-5)
- Dimethyl-(2-piperidin-2-yl-ethyl)-amine (CAS 60717-49-9)
- 3-amino-1-[(tert-butoxy)carbonyl]azetidine-3-carboxylic acid (CAS 1262412-13-4)
- 1-(4-Ethoxyphenyl)-1h-pyrrole-2-carbaldehyde (CAS 86454-34-4)
- Loratadine Impurity 94 (CAS CATO-C4X-142694)
- Ethylene-d4-diamine 2HCl (CAS 34334-71-9)
- Dendroaspis Natriuretic Peptide (CAS 255721-52-9)
Why CATO?
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