4-{[2-(4-chlorobenzoyl)-5-(trifluoromethyl)pyridin-3-yl]oxy}phenol CAS 338959-85-6
| CAS No. | 338959-85-6 |
| Molecular Formula | C19H11ClF3NO3 |
| Molecular Weight | 393.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-{[2-(4-chlorobenzoyl)-5-(trifluoromethyl)pyridin-3-yl]oxy}phenol.
CATO supplies 4-{[2-(4-chlorobenzoyl)-5-(trifluoromethyl)pyridin-3-yl]oxy}phenol (CAS 338959-85-6), a certified reference material (molecular formula C19H11ClF3NO3, MW 393.74 g/mol) for analytical method development and quality control.
Based on its molecular formula C19H11ClF3NO3, 4-{[2-(4-chlorobenzoyl)-5-(trifluoromethyl)pyridin-3-yl]oxy}phenol contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 393.74 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-{[2-(4-chlorobenzoyl)-5-(trifluoromethyl)pyridin-3-yl]oxy}phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H11ClF3NO3 |
| Molecular Weight | 393.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related chlorobenzoyl Standards
- 6-(4-Chlorobenzoyl)-4-(3-chlorophenyl)quinolin-2(1H)-one (CAS 192187-32-9)
- 5-(4-(4-Chlorobenzoyl)piperazin-1-yl)-6-phenylpyridazin-3(2H)-one (CAS 477863-44-8)
- 1-(4-Chlorobenzoyl)-4-{[(4-chlorophenyl)sulfanyl]methyl}piperidin-4-ol (CAS 478248-10-1)
- 3-[1-(3-Chlorobenzoyl)piperidin-4-yl]-4-(4-methylphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775357-62-4)
- N'-(3-chlorobenzoyl)-1-(3-fluorobenzyl)piperidine-4-carbohydrazide (CAS 478259-07-3)
- 4-(4-Chlorobenzoyl)-1-(furan-2-ylmethyl)-3-hydroxy-5-(thiophen-2-yl)-1H-pyrrol-2(5H)-one (CAS 618074-50-3)
- 4-[5-(4-Chlorobenzoyl)-3-(pyridin-2-yl)thiophen-2-yl]morpholine (CAS 339023-17-5)
- (E)-({4-[4-(3-chlorobenzoyl)piperazin-1-yl]-3-nitrophenyl}methylidene)(methoxy)amine (CAS 383147-23-7)
Recommended Standards
- Iodoform (CAS 75-47-8)
- Ethyl 2-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetate (CAS 860789-12-4)
- 5-((4-Bromophenyl)thio)-4-(chloromethyl)-1-methyl-3-phenyl-1H-pyrazole (CAS 318959-24-9)
- N-(3-chloro-4-(pyrimidin-2-yloxy)phenyl)-3-(trifluoromethyl)benzamide (CAS 338413-33-5)
- 4-Amino-6-chloro-5-iodo-2-methylpyridazin-3(2H)-one (CAS 1445994-01-3)
- (2,2-Dimethylcyclobutyl)methanol (CAS 65502-62-7)
- 3,6-dihydroxy-2-methyl-3,4-dihydroquinazolin-4-one (CAS 1322604-74-9)
- N1-(1,1,1-triphenyl-lambda5-phosphanylidene)-3,5-di(trifluoromethyl)aniline (CAS 628301-58-6)
- 2-Bromo-1-(4-methoxy-2,5-dimethylphenyl)ethan-1-one (CAS 879053-30-2)
- 2-(Cyclopentylmethoxy)aniline (CAS 640767-46-0)
- Gefitinib Impurity 29 (CAS 861453-16-9)
- tert-Butyl ((3-bromo-6-methylpyridin-2-yl)methyl)carbamate (CAS 2585650-04-8)
- 2-Imino-10-methyltetrahydro-8a,3-(epoxymethano)chromene-3,4,4(2H,4aH)-tricarbonitrile (CAS 95059-21-5)
- Casein kinase II peptide Substrate (CAS 154444-98-1)
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