5-Chloro-1-(3-chlorobenzyl)-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide CAS 338977-40-5
| CAS No. | 338977-40-5 |
| Molecular Formula | C19H12Cl2F2N2O2 |
| Molecular Weight | 409.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-1-(3-chlorobenzyl)-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide.
5-Chloro-1-(3-chlorobenzyl)-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 338977-40-5), molecular formula C19H12Cl2F2N2O2 and molecular weight 409.21 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C19H12Cl2F2N2O2, 5-Chloro-1-(3-chlorobenzyl)-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 409.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-1-(3-chlorobenzyl)-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H12Cl2F2N2O2 |
| Molecular Weight | 409.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-N-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)hydrazine-1-carbonothioyl)benzamide (CAS 883038-95-7)
- 5-Chloro-1-(4-chlorobenzyl)-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 339024-72-5)
- 3-Chloro-2-[2-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-5-(trifluoromethyl)pyridine (CAS 1092345-64-6)
- 7-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidine (CAS 1400872-28-7)
- 3-Chloro-2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-6-yl]-5-(trifluoromethyl)pyridine (CAS 338953-33-6)
- 6-Chloro-3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H,4H-benzo[h]quinolin-4-one (CAS 478033-81-7)
- 2-chloro-4-(2-chloro-N-cyclopropyl-4-(cyclopropylamino)pyrimidine-5-carboxamido)pyrimidine-5-carboxylic acid (CAS CATO-C3D-262478)
- N-(3-chloro-4-methoxybenzyl)-3-(2-chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxamide (CAS 478259-46-0)
Recommended Standards
- 1-[(2,6-Dichlorophenyl)methyl]-N-(2,4-difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338755-02-5)
- N-(3,5-dichlorophenyl)-1-(3,4-difluorobenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 242797-42-8)
- 1-(2,6-Dichlorobenzyl)-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 339008-61-6)
- Tepotinib impurity 16 (CAS CATO-C4X-337416)
- 4-Methoxy-N-{1-[(3-methoxyphenyl)methyl]-5,6-dimethyl-1H-1,3-benzodiazol-4-yl}benzene-1-sulfonamide (CAS 338955-15-0)
- Methyl 2,3,4-Tri-O-benzyl-α-D-glucuronic Acid, Benzyl Ester (CAS 142797-33-9)
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- (S)-3-Methyl-2-(pyrimidin-5-ylamino)butanoic acid (CAS 1007881-27-7)
- 2-{N-methyl-1-[1-methyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]formamido}acetic acid (CAS 1152952-90-3)
- Methyl 2-[(5-bromopyridin-2-yl)amino]acetate (CAS 620175-59-9)
- Biotinyl-CBP501 Affinity Peptide trifluoroacetate salt (CAS 2022956-39-2)
Why CATO?
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