2-chloro-4-(2-chloro-N-cyclopropyl-4-(cyclopropylamino)pyrimidine-5-carboxamido)pyrimidine-5-carboxylic acid CAS CATO-C3D-262478
| CAS No. | CATO-C3D-262478 |
| Molecular Formula | C16H14Cl2N6O3 |
| Molecular Weight | 409.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-chloro-4-(2-chloro-N-cyclopropyl-4-(cyclopropylamino)pyrimidine-5-carboxamido)pyrimidine-5-carboxylic acid (CAS CATO-C3D-262478), molecular formula C16H14Cl2N6O3 and molecular weight 409.23 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-chloro-4-(2-chloro-N-cyclopropyl-4-(cyclopropylamino)pyrimidine-5-carboxamido)pyrimidine-5-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 409.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14Cl2N6O3 |
| Molecular Weight | 409.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related chloro Standards
- N-(3-chloro-4-methoxybenzyl)-3-(2-chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxamide (CAS 478259-46-0)
- 4-Chloro-N-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)hydrazine-1-carbonothioyl)benzamide (CAS 883038-95-7)
- 5-Chloro-1-(3-chlorobenzyl)-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 338977-40-5)
- 5-Chloro-1-(4-chlorobenzyl)-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 339024-72-5)
- 1785763-83-8 3,5-Bis[(2-chloro-1,3-thiazol-5-yl)methyl]-N-nitro-1,3,5-oxadiazinan-4-imine (CAS 1785763-83-8)
- N-(4-Chloro-3-nitrophenyl)-2-[4-(3-chlorophenyl)piperazin-1-yl]acetamide (CAS 329779-16-0)
- 3-Chloro-2-[2-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-5-(trifluoromethyl)pyridine (CAS 1092345-64-6)
- 7-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidine (CAS 1400872-28-7)
Recommended Standards
- HA 14-1, 95% (CAS 65673-63-4)
- Resmetirom impurity 136 (CAS CATO-C4X-2912136)
- (ΑR,4R)-rel-2-amino-6-bromo-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid, ethyl ester (CAS 927635-64-1)
- Resmetirom Impurity 24 (CAS 2987937-25-5)
- 1-Methyl-4-piperidinol hydrochloride 1-methyl-4-piperidone hydrochloride 34737-83-2 (CAS 34737-83-2)
- 2-(Benzylamino)quinoline-4-carboxylic acid (CAS 1097017-44-1)
- rac-(2R,3R)-1-cyclopropyl-2-(1,5-dimethyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1969288-56-9)
- Fluoxetine Impurity 19 (CAS 1026723-45-4)
- tert-Butyl 4-((((benzyloxy)carbonyl)amino)methyl)benzoate (CAS 220851-46-7)
- N-((1-methyl-5-morpholino-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)hexanamide (CAS 956184-34-2)
- Tucatinib Impurity N5 (CAS 4706-13-2)
- Tert-butyl 3-oxo-4-(tetrahydro-2H-pyran-4-yl)piperazine-1-carboxylate (CAS 1400755-13-6)
- (E)-4-Fluorobenzaldehyde oxime (CAS 7304-35-0)
- Des-Gln24-Tirzepatide (CAS CATO-CPTD788949)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com