Methyl 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-5-oxopyrrolidine-3-carboxylate CAS 339106-08-0
| CAS No. | 339106-08-0 |
| Molecular Formula | C12H11ClF3N3O3 |
| Molecular Weight | 337.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 337.68 g/mol gives Methyl 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-5-oxopyrrolidine-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-5-oxopyrrolidine-3-carboxylate (CAS 339106-08-0), molecular formula C12H11ClF3N3O3 and molecular weight 337.68 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Methyl 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-5-oxopyrrolidine-3-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 337.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Methyl 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-5-oxopyrrolidine-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H11ClF3N3O3 |
| Molecular Weight | 337.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 2-(2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-methylhydrazine-1-carbonyl)cyclopropane-1-carboxylic acid (CAS 1024308-67-5)
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- 5-(4-Chloro-3-nitrophenyl)-3-(2,6-difluorophenyl)-1,2,4-oxadiazole (CAS 1710644-11-3)
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- 5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-4,5-dihydroisoxazole-3-carbohydrazide (CAS 251310-32-4)
- 2-chloro-3-pyridyl 4-(trifluoromethyl)benzene-1-sulphonate (CAS 219930-36-6)
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Recommended Standards
- 4-((6-(Trifluoromethyl)pyridin-2-yl)oxy)benzenesulfonyl chloride (CAS 1210732-06-1)
- 4-((4-(Trifluoromethyl)pyridin-2-yl)oxy)benzenesulfonyl chloride (CAS 1227955-11-4)
- 5-(2,2,2-Trifluoroacetamido)naphthalene-1-sulfonyl chloride (CAS 160206-27-9)
- N-tert-Butyl-2-chloro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 2377610-51-8)
- Ethyl 11(E)-eicosenoate (CAS 2692622-85-6)
- N-[2-[[6-(2,6-Dichloro-3,5-dimethoxyphenyl)-2-quinazolinyl]amino]-3-methylphenyl]acrylamide (CAS 1538604-68-0)
- (S)-2-Amino-5-phosphonopentanoic acid hydrochloride (CAS 95306-96-0)
- Pimavanserin Impurity 18 (CAS CATO-C4X-193818)
- N-(4-(((4-(3-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)ureido)naphthalen-1-yl)oxy)methyl)pyridin-2-yl)-2-methoxyacetamide (CAS 1220626-82-3)
- 2-((3,5-Dichlorophenyl)thio)ethan-1-ol (CAS 101079-86-1)
- 5-(Tert-butyl)-2-propoxybenzaldehyde (CAS 883515-73-9)
- 4-Fluoro-5-(o-tolyl)-1H-pyrazole-3-carboxylic acid (CAS 1404364-21-1)
- 2-Bromo-1-cyclopropyl-4-nitrobenzene (CAS 57807-35-9)
- Peptide Impurity (CAS CATO-CPTD788810)
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