Carbamazepine Impurity 11 CAS 33948-20-8
| CAS No. | 33948-20-8 |
| Molecular Formula | C15H11BrClNO |
| Molecular Weight | 336.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Carbamazepine Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Carbamazepine Impurity 11 (CAS 33948-20-8), a pharmacopoeial impurity reference standard (molecular formula C15H11BrClNO, MW 336.61 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Carbamazepine Impurity 11 (C15H11BrClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C15H11BrClNO |
| Molecular Weight | 336.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Carbamazepine Standards
- Carbamazepine Impurity 17 (CAS CATO-C4X-118117)
- Carbamazepine Impurity 12 (CAS 143667-53-2)
- Carbamazepine Impurity 22 (CAS CATO-C4X-118122)
- Carbamazepine EP Impurity G (CAS 59690-97-0)
- Carbamazepine Impurity 19 (CAS CATO-C4X-118119)
- Carbamazepine Impurity 23 (CAS CATO-C4X-118123)
- Carbamazepine Impurity 15 (CAS CATO-C4X-118115)
- Carbamazepine Impurity 32 (CAS 40421-05-4)
Recommended Standards
- N-(4-bromo-2-chlorophenyl)-3-phenylprop-2-enamide (CAS 892722-20-2)
- Bromfenac Impurity 15 (CAS CATO-C4X-200215)
- N-(3-Bromophenyl)-3-(4-chlorophenyl)acrylamide (CAS 304672-82-0)
- 3-n-Octadecylthiophene (CAS 104934-54-5)
- Amisulpride Impurity 56 (CAS CATO-C4X-104556)
- Uridine Impurity 26 (CAS 303197-29-7)
- Bisoprolol Impurity 63 (CAS 704200-67-9)
- 2-(Piperidin-4-yloxy)quinoxaline hydrochloride (CAS 1185309-98-1)
- 1-(3-Bromopropyl)-1,2,3,4-tetrahydronaphthalene (CAS 161923-63-3)
- 2-(4-Chlorophenyl)-5-ethyl-5-methylmorpholine (CAS 1342788-82-2)
- 3,4-Dihydroxycyclohexanecarboxylic acid (CAS 32746-99-9)
- rac-(2R,6S)-2-ethyl-6-methylpiperazine (CAS 2031242-31-4)
- Benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate hydrochloride (CAS 1255098-65-7)
- Mast Cell Degranulating (MCD) Peptide (CAS 32908-73-9)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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