4-(2,4-Dichlorophenyl)-2-hydroxy-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile CAS 341964-44-1
| CAS No. | 341964-44-1 |
| Molecular Formula | C19H9Cl2F3N2O |
| Molecular Weight | 409.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(2,4-Dichlorophenyl)-2-hydroxy-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(2,4-Dichlorophenyl)-2-hydroxy-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 341964-44-1), molecular formula C19H9Cl2F3N2O and molecular weight 409.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(2,4-Dichlorophenyl)-2-hydroxy-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (C19H9Cl2F3N2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H9Cl2F3N2O |
| Molecular Weight | 409.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorophenyl Standards
- 3-[1-(2,4-Dichlorophenyl)-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]pyridine (CAS 306977-32-2)
- 6-(3,4-Dichlorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile (CAS 252059-70-4)
- 6-(3,4-Dichlorophenyl)-2-hydroxy-4-[2-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 478261-50-6)
- 1-[(2,6-Dichlorophenyl)methyl]-N-(2,4-difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338755-02-5)
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Recommended Standards
- 4-({[(2,6-dichlorobenzoyl)amino]carbonyl}amino)-3-fluorobenzenesulphonyl fluoride (CAS 284674-48-2)
- 3-Chloro-2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-6-yl]-5-(trifluoromethyl)pyridine (CAS 338953-33-6)
- 6-Chloro-3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H,4H-benzo[h]quinolin-4-one (CAS 478033-81-7)
- 3-(4-Chlorophenyl)-1-(6-chloropyridin-2-yl)-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine (CAS 303152-01-4)
- 1-(2-Aminophenyl)propan-2-ol (CAS 65826-91-7)
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