4-Chloro-2-fluorophenol CAS 348-62-9
| CAS No. | 348-62-9 |
| Molecular Formula | C6H4ClFO |
| Molecular Weight | 146.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-2-fluorophenol.
4-Chloro-2-fluorophenol (CAS 348-62-9) is a high-purity analytical reference standard with the molecular formula C6H4ClFO and a molecular weight of 146.55 g/mol.
The molecular framework of 4-Chloro-2-fluorophenol (C6H4ClFO) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-2-fluorophenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4ClFO |
| Molecular Weight | 146.55 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
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Recommended Standards
- 4-Amino-2-chloro-5-fluoropyridine (CAS 89510-90-7)
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- 3-Chloro-5-fluorophenol (CAS 202982-70-5)
- 5-Chloro-2-fluoro-4-methylpyrimidine (CAS 99429-16-0)
- 2-(6-Chloro-2-fluoro-3-methylphenyl)acetaldehyde (CAS 1256477-02-7)
- 4,7-Bis(5-bromo-2-thienyl)-2-n-octyl-2H-benzotriazole (CAS 1254062-41-3)
- 3-Amino-6-fluoropyridazine, 97% (CAS 108784-42-5)
- 4-(4-Fluorophenyl)-1-isopropyl-1H-indole-3-carbaldehyde (CAS 1350760-31-4)
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- 2-(tert-Butyl)-5-hydroxy-4-methylpyridazin-3(2H)-one (CAS 104010-22-2)
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- 3-(3,4-Dimethoxyphenyl)-N-(2-(2-methyl-1H-indol-1-yl)ethyl)acrylamide (CAS 1164541-81-4)
- Phthalate-Mix 10 (CAS CATO-MPAE111710-HE)
- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com