Folic Acid Hydrate EP Impurity B CAS 35011-47-3
| CAS No. | 35011-47-3 |
| Molecular Formula | C4H7N5O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Folic Acid Hydrate EP Impurity B is closely related to a carbohydrate-derived structure, an amide group, a sulfone group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Folic Acid Hydrate EP Impurity B (CAS 35011-47-3, C4H7N5OH2O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C4H7N5OH2O4S, Folic Acid Hydrate EP Impurity B contains a carbohydrate-derived structure, an amide group, a sulfone group; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 239.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Folic Acid Hydrate EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H7N5O H2O4S |
| Molecular Weight | 239.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Folic Standards
- Folic acid EP Impurity B (CAS 1004-75-7)
- Folic Acid Hydrate (CAS 1174277-30-5)
- Folic Acid Impurity 45 (CAS 1182291-60-6)
- Folic Acid EP Impurity D (CAS 119-24-4)
- Folic Acid-13C5 (CAS 1207282-75-4)
- Folic Acid EP Impurity E (CAS 1391068-26-0)
- Folic Acid EP Impurity F (CAS 1391194-56-1)
- Folic Acid EP Impurity F HCl (CAS 1391194-56-1(free base))
Recommended Standards
- Nintedanib Impurity 105 (CAS CATO-C4X-1814105)
- Atrasentan Impurity 42 (CAS 1349623-84-2)
- Betamethasone Impurity 137 (CAS CATO-C4X-1437137)
- 3,3',5,5'-Tetra(1H-pyrazol-4-yl)-1,1'-biphenyl (CAS 2630939-88-5)
- 1-(azetidin-3-yl)ethan-1-one; trifluoroacetic acid (CAS 1309208-83-0)
- 4-Nitro-2-(trifluoromethyl)benzamide (CAS 22227-54-9)
- 2-(2-Isopropoxyethyl)pyrrolidine (CAS 1344319-24-9)
- 2-(3,4-Difluorophenyl)butanoic acid (CAS 1226167-09-4)
- 1-(3,4-Difluorophenyl)-3-(1-methyl-1H-indol-3-yl)urea (CAS 922939-46-6)
- Polymyxin B nonapeptide (CAS 86408-36-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com