Dotinurad Impurity 77 CAS 35458-33-4
| CAS No. | 35458-33-4 |
| Molecular Formula | C7H4Cl2O3 |
| Molecular Weight | 207.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dotinurad Impurity 77 (CAS 35458-33-4) is a certified pharmaceutical impurity reference standard with the molecular formula C7H4Cl2O3 and a molecular weight of 207.01 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Dotinurad Impurity 77 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 207.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Dotinurad Impurity 77 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4Cl2O3 |
| Molecular Weight | 207.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ＞95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
Related Dotinurad Standards
- Dotinurad Impurity 193 (CAS CATO-C4X-2494193)
- Dotinurad Impurity 85 (CAS 80547-63-3)
- Dotinurad Impurity 170 (CAS 50910-60-6)
- Dotinurad Impurity 211 (CAS 70679-89-9)
- Dotinurad Impurity 214 (CAS CATO-C4X-2494214)
- Dotinurad Impurity 67 (CAS 39884-80-5)
- Dotinurad Impurity 257 (CAS CATO-C4X-2494257)
- Dotinurad Impurity 137 (CAS 63001-37-6)
Recommended Standards
- Methyl 4,6-dichloropyrimidine-5-carboxylate (CAS 87600-71-3)
- 3,5-Dichloro-4-hydroxybenzoic Acid (CAS 3336-41-2)
- Methyl 4,6-Dichloropyrimidine-2-carboxylate (CAS 811450-22-3)
- 3,5-Dichlorosalicylic Acid (CAS 320-72-9)
- Oxybuprocaine Impurity 8 (CAS CATO-C4X-12278)
- Trelagliptin Impurity 68 (CAS CATO-C4X-104668)
- Tucatinib Impurity 33 (CAS CATO-C4X-260533)
- (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopiperidin-3-yl)propanoate (CAS 1442483-69-3)
- 1-(3-Chlorobenzyl)-3-(5-((2,4-dichlorobenzyl)thio)-1,3,4-oxadiazol-2-yl)pyridin-2(1H)-one (CAS 477852-94-1)
- Strontium Chromate (CAS 7789-06-2)
- 1-(Dichloromethyl)-2-(trichloromethyl)benzene (CAS 2741-57-3)
- 4-Oxa-6-azaspiro[2.4]heptan-5-one (CAS 1238704-57-8)
- Nω-Methyl L-Norarginine (CAS 186308-99-6)
- Semaglutide impurity 214 (CAS CATO-C4X-2226214)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com