Dotinurad Impurity 214 CAS CATO-C4X-2494214
| CAS No. | CATO-C4X-2494214 |
| Molecular Formula | C9H7ClO4 |
| Molecular Weight | 214.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dotinurad Impurity 214 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Dotinurad Impurity 214 (CAS CATO-C4X-2494214), a pharmacopoeial impurity reference standard (molecular formula C9H7ClO4, MW 214.60 g/mol) used for the identification and quantification of trace impurities in APIs.
Dotinurad Impurity 214 (C9H7ClO4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Dotinurad Impurity 214 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7ClO4 |
| Molecular Weight | 214.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Dotinurad Standards
- Dotinurad Impurity 211 (CAS 70679-89-9)
- Dotinurad Impurity 137 (CAS 63001-37-6)
- Dotinurad Intermediate 2 (CAS 37908-97-7)
- Dotinurad Impurity 77 (CAS 35458-33-4)
- Dotinurad Impurity 193 (CAS CATO-C4X-2494193)
- Dotinurad Impurity 85 (CAS 80547-63-3)
- Dotinurad Impurity 170 (CAS 50910-60-6)
- Dotinurad Impurity 53 (CAS CATO-C4X-249453)
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