Regorafenib Impurity 21 CAS 35592-96-2
| CAS No. | 35592-96-2 |
| Molecular Formula | C7H3Cl4NO2 |
| Molecular Weight | 274.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Regorafenib Impurity 21 (CAS 35592-96-2), a certified reference material (molecular formula C7H3Cl4NO2, MW 274.92 g/mol) for analytical method development and quality control.
Based on its molecular formula C7H3Cl4NO2, Regorafenib Impurity 21 contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 274.92 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Regorafenib Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3Cl4NO2 |
| Molecular Weight | 274.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Regorafenib Standards
- Regorafenib Impurity 63 (CAS CATO-C4X-104763)
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- Regorafenib Impurity 71 (CAS CATO-C4X-104771)
- Regorafenib Impurity 31 (CAS CATO-C4X-104731)
- Regorafenib Impurity 43 (CAS 1798046-84-0)
- Regorafenib Impurity 40 (CAS 2711-18-4)
- Regorafenib Impurity 36 (CAS 864245-61-4)
- Regorafenib EP Impurity A (CAS 757251-39-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com