Dexamethasone-d5 CAS 358731-91-6
| CAS No. | 358731-91-6 |
| Molecular Formula | - |
| Molecular Weight | 397.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 397.49 g/mol gives Dexamethasone-d5 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Dexamethasone-d5 (CAS 358731-91-6), a certified reference material (molecular formula C22H24D5FO5, MW 397.49 g/mol) for analytical method development and quality control.
The molecular framework of Dexamethasone-d5 (C22H24D5FO5) is characterized by deuterium isotope labeling, a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Dexamethasone-d5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H24D5FO5 |
| Molecular Weight | 397.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone EP Impurity B Hydrochloride (CAS 956901-32-9)
- Dexamethasone-d4 (CAS 50-02-2(Unlabelled))
- Dexamethasone EP Impurity H (CAS 10106-41-9)
- Dexamethasone Impurity 116 (CAS 107419-73-8)
- Dexamethasone-d3 (CAS CATO-CCAD301835)
- Dexamethasone EP Impurity C (CAS 426-17-5)
- Dexamethasone Impurity 24 (CAS 24510-54-1)
- Dexamethasone-4¸6α¸21¸21-[d4] (CAS 2483831-63-4)
Recommended Standards
- Brinzolamide Impurity 27 (CAS CATO-C4X-194027)
- Betamethasone-d5 (CAS CATO-CCAD301382)
- Eletriptan Impurity 2 (CAS CATO-C4X-18872)
- NH-bis(m-PEG4) (CAS 123852-08-4)
- (E)-[(2H-1,3-Benzodioxol-5-yl)methylidene]amino 4-methylbenzoate (CAS 306732-19-4)
- 1,3-Diiodopropan-2-ol (CAS 534-08-7)
- 5-(Tert-butyl)-3-methyl-[1,2,4]triazolo[4,3-a]pyrimidine-7-carboxylic acid (CAS 890621-55-3)
- 3-(Chlorosulfonyl)-4,5-dimethylbenzoic acid (CAS 151104-64-2)
- (E)-4-bromo-2-fluorobenzaldehyde oxime (CAS 202865-64-3)
- 4-(2-Hydroxy-2,2-diphenylethyl)benzonitrile (CAS 10517-66-5)
- 3,4-Dihydroxythiobenzamide (CAS 138038-57-0)
- 6-(3-Amino-4-methylphenyl)pyridazin-3-ol (CAS 1030563-11-1)
- Methyl 4-(2-hydroxyethoxy)benzoate (CAS 3204-73-7)
- Tau Peptide (307-321) trifluoroacetate salt (CAS 330456-50-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com