Dexamethasone EP Impurity C CAS 426-17-5
| CAS No. | 426-17-5 |
| Molecular Formula | C22H31FO5 |
| Molecular Weight | 394.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, Dexamethasone EP Impurity C is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 394.48 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Dexamethasone EP Impurity C (CAS 426-17-5, C22H31FO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dexamethasone EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H31FO5 |
| Molecular Weight | 394.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone-d3 (CAS CATO-CCAD301835)
- Dexamethasone Impurity 116 (CAS 107419-73-8)
- Dexamethasone-d4 (CAS 50-02-2(Unlabelled))
- Dexamethasone-4¸6α¸21¸21-[d4] (CAS 2483831-63-4)
- Dexamethasone (CAS 50-02-2)
- Dexamethasone EP Impurity A (CAS CATO-C4X-11651)
- Dexamethasone Impurity 62 (CAS CATO-C4X-116562)
- Dexamethasone impurity 67 (CAS CATO-C4X-116567)
Recommended Standards
- Ethyl 2-((3-(4-fluorophenyl)-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)butanoate (CAS 687562-47-6)
- Betamethasone Impurity 86 (CAS 560-34-9)
- 3-Hydroxy Dexamethasone (Alpha/Beta-Mixture) (CAS 922713-68-6)
- (Z)-5-Amino-3-oxo-7-(thiophen-2-yl)-2-(thiophen-2-ylmethylene)-2,3-dihydro-7H-thiazolo[3,2-a]pyridine-6,8-dicarbonitrile (CAS 106642-94-8)
- Roflumilast Impurity 49 (CAS CATO-C4X-108449)
- Olaparib Impurity 35 (CAS CATO-C4X-113535)
- Rociletinib Impurity N1 (CAS 165897-63-2)
- 4-((Diisopropylamino)methyl)benzenethiol (CAS 1443329-51-8)
- (2-Bromo-1,1-difluoroethyl)benzene (CAS 108661-89-8)
- Dimethyl 2,2'-((oxybis(1,1,2,2-tetrafluoroethane-2,1-diyl))bis(oxy))bis(2,2-difluoroacetate) (CAS 35910-59-9)
- GSK2801 (CAS 1619994-68-1)
- 2-Chloro-5-(piperidine-1-carbonyl)aniline (CAS 91766-96-0)
- 1,3-Bis(4-methylbenzyl)urea (CAS 37389-92-7)
- Des-Phe22-Tirzepatide (CAS CATO-CPTD788951)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com