Samidorphan impurity 1 CAS 361525-83-9
| CAS No. | 361525-83-9 |
| Molecular Formula | C23H28N2O5 |
| Molecular Weight | 412.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Samidorphan impurity 1 (C23H28N2O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Samidorphan impurity 1 (CAS 361525-83-9) is a certified pharmaceutical impurity reference standard with the molecular formula C23H28N2O5 and a molecular weight of 412.48 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Samidorphan impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H28N2O5 |
| Molecular Weight | 412.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Samidorphan Standards
- Samidorphan Impurity 3 (CAS CATO-C4X-33093)
- Samidorphan Impurity 12 (CAS CATO-C4X-330912)
- Samidorphan (CAS 852626-89-2)
- Samidorphan Impurity 10 (CAS 886588-56-3)
- Samidorphan (CAS 421552-35-4)
- Samidorphan Impurity 11 (CAS 886588-57-4)
- Samidorphan Impurity 4 (CAS CATO-C4X-33094)
- Samidorphan Impurity 8 (CAS CATO-C4X-33098)
Recommended Standards
- Tolvaptan Impurity 89 (CAS 137977-65-2)
- Z-Leu-Phe-OH (CAS 6401-63-4)
- Tolvaptan Impurity 124 (CAS CATO-C4X-1955124)
- 2-(Benzo[d]thiazol-2-ylthio)-N-(2-(3-(furan-2-yl)-6-oxopyridazin-1(6H)-yl)ethyl)acetamide (CAS 1207007-45-1)
- Regorafenib EP Impurity D (CAS 2438857-80-6)
- Butylphthalide Impurity 41 Potassium (CAS 952412-99-6)
- Terbinafine EP Impurity E (CAS 934365-23-8)
- 946700-52-3 (2-Furylmethyl)(1H-indol-5-ylmethyl)amine MFCD13248780 (CAS 946700-52-3)
- Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 (CAS 158584-09-9)
- Methyl 2-(1-Methyl-4-piperidyl)acetate (CAS 95533-25-8)
- Methyl 2,6-difluoro-4-(2-oxoethyl)benzoate (CAS 2222118-49-0)
- 1-Ethyl-1H-pyrrole-2-carboxaldehyde (CAS 2167-14-8)
- N-(Amino-PEG5)-N-bis(PEG4-acid) (CAS 2093152-86-2)
- Tetrapeptide-3 (CAS 827306-97-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com