Etoposide impurity 21 CAS CATO-C4X-202421
| CAS No. | CATO-C4X-202421 |
| Molecular Formula | C23H21ClO9 |
| Molecular Weight | 476.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 476.86 g/mol gives Etoposide impurity 21 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Etoposide impurity 21 (CAS CATO-C4X-202421) is a certified pharmaceutical impurity reference standard with the molecular formula C23H21ClO9 and a molecular weight of 476.86 g/mol.
The molecular framework of Etoposide impurity 21 (C23H21ClO9) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Etoposide impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H21ClO9 |
| Molecular Weight | 476.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Etoposide Standards
- Etoposide Impurity 27 (CAS 101648-62-8)
- Etoposide Impurity 31 (CAS CATO-C4X-202431)
- Etoposide EP Impurity H (CAS 102306-95-6)
- Etoposide Impurity 25 (CAS CATO-C4X-202425)
- Etoposide Impurity 35 (CAS CATO-C4X-202435)
- Etoposide Impurity 38 (CAS CATO-C4X-202438)
- Etoposide EP Impurity J (CAS 118356-05-1)
- Etoposide EP Impurity M (CAS 518-28-5)
Recommended Standards
- Meclocycline (CAS 2013-58-3)
- (3-Chloro-4-methoxyphenyl)(1-(trifluoromethyl)spiro[benzo[b]pyrrolo[1,2-d][1,4]oxazine-4,4'-piperidin]-1'-yl)methanone (CAS 1433633-45-4)
- Temazepam Glucuronide (CAS 3703-53-5)
- N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N'-methyl-2,3-diphenylisoxazolidine-5-carbohydrazide (CAS 339102-24-8)
- Nizatidine EP Impurity H (CAS 27507-28-4)
- Atorvastatin Impurity 63 (CAS 196085-85-5)
- Osimertinib Impurity 30 (CAS CATO-C4X-204530)
- 4-Methyl-1-(4-methylphenyl)pentane-1,3-dione (CAS 100612-22-4)
- Benzoic Acid Isobutyl Ester (CAS 120-50-3)
- N-Nitroso Sertraline D3 (CAS CATO-C4X-134456)
- methyl({[2-(prop-2-yn-1-yloxy)phenyl]methyl})amine hydrochloride (CAS 1258640-56-0)
- (1S,2S)-1-((tert-Butoxycarbonyl)amino)-2-vinylcyclopropanecarboxylic acid (CAS 259221-77-7)
- Eriochrome blue-black B (C.I. 14640), metal indicator (CAS 3564-14-5)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com