Erythromycin Impurity 50 CAS 37152-22-0
| CAS No. | 37152-22-0 |
| Molecular Formula | C38H69NO13 |
| Molecular Weight | 747.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Erythromycin Impurity 50 (CAS 37152-22-0, C38H69NO13) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Erythromycin Impurity 50 (C38H69NO13) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C38H69NO13 |
| Molecular Weight | 747.95 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 1 |
Related Erythromycin Standards
- Erythromycin EP Impurity L (CAS 127955-44-6)
- Erythromycin EP Impurity C (CAS 41451-91-6)
- (9Z)-Erythromycin A Oxime (CAS 134931-01-4)
- Erythromycin Z Oxime (CAS CATO-C4X-100129)
- Erythromycin Impurity 39 (CAS CATO-C4X-100139)
- Erythromycin thiocyanate impurity C reduced derivative (CAS CATO-C4X-100167)
- Erythromycin A 9-Oxime (Mixture of Z and E Isomers) (CAS 13127-18-9)
- Erythromycin thiocyanate impurity A rearranged derivative (CAS CATO-C4X-100173)
Recommended Standards
- Eribulin Impurity 3 (CAS CATO-C4X-26503)
- Clarithromycin impurity 14 (CAS 138109-92-9)
- Eribulin Impurity 2 (CAS 1534341-96-2)
- Clarithromycin (CAS 81103-11-9)
- Afoxolaner impurity 7 (CAS CATO-C4X-31377)
- Tiotropium Bromide Impurity 31 (CAS 54725-49-4)
- Tegoprazan Impurity 105 (CAS CATO-C4X-2297105)
- 2-Chloro-3-fluoro-5-methoxypyridine (CAS 1211588-72-5)
- tert-Butyl 3-(methoxymethyl)piperidine-3-carboxylate (CAS 2137647-95-9)
- 2-(2-(3-Fluorophenoxy)ethyl)-1,3-dioxane (CAS 1443338-53-1)
- 2-[Isopropyl-((S)-1-methyl-pyrrolidin-3-yl)-amino]-ethanol (CAS 1354007-06-9)
- 2,5-Dioxopyrrolidin-1-yl octanoate (CAS 14464-30-3)
- Rhodamine 700 (CAS 63561-42-2)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
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