Sildenafil Impurity 27 CAS 372089-76-4
| CAS No. | 372089-76-4 |
| Molecular Formula | C17H21N5O4S |
| Molecular Weight | 391.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Sildenafil Impurity 27 (C17H21N5O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 391.44 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Sildenafil Impurity 27 (CAS 372089-76-4), a pharmacopoeial impurity reference standard (molecular formula C17H21N5O4S, MW 391.44 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H21N5O4S |
| Molecular Weight | 391.44 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Sildenafil Standards
- Sildenafil Impurity 45 (CAS 1391054-00-4)
- Sildenafil Impurity 76 (CAS CATO-C4X-112876)
- Sildenafil EP Impurity D (CAS 1357931-55-5)
- Sildenafil Impurity 5 (CAS 1058653-74-9)
- Sildenafil Impurity 9 (CAS 139756-31-3)
- Sildenafil Impurity 8 (CAS 139756-27-7)
- Sildenafil Impurity 261 (CAS CATO-C4X-1128261)
- Sildenafil Impurity 52 (CAS CATO-C4X-112852)
Recommended Standards
- Rabeprazole EP Impurity I (CAS 924663-37-6)
- Torasemide Impurity 45 (CAS CATO-C4X-183645)
- Vardenafil Impurity 67 (CAS 448184-60-9)
- Prazosin-D8 (CAS 1006717-55-0)
- Empagliflozin Impurity 168 (CAS CATO-C4X-1065168)
- Vitamin K1 Impurity 5 (CAS 483-55-6)
- Palonosetron Impurity 47 (CAS 2216746-63-1(free base))
- 2-((6-(1H-Pyrazol-1-yl)pyridazin-3-yl)thio)-N-(thiophen-2-ylmethyl)acetamide (CAS 1351642-58-4)
- 7-Oxa-1-azaspiro[3.6]Decane (CAS 1214875-16-7)
- 2-(2-Aminopyrimidin-4-yl)-4-chlorophenol (CAS 925003-43-6)
- (3-Bromo-4-methylpyridin-2-yl)methanamine (CAS 1443288-53-6)
- 1-Methyl-N-((2-methylthiazol-4-yl)methyl)-1H-pyrazol-3-amine (CAS 1183526-35-3)
- Levomequitazine (CAS 88598-74-7)
- Semaglutide Impurity 123 (CAS 71997-93-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com