Iohexol EP Impurity L CAS 37441-29-5
| CAS No. | 37441-29-5 |
| Molecular Formula | C8H2Cl2I3NO2 |
| Molecular Weight | 595.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Iohexol EP Impurity L (CAS 37441-29-5), a pharmacopoeial impurity reference standard (molecular formula C8H2Cl2I3NO2, MW 595.73 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Iohexol EP Impurity L (C8H2Cl2I3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 595.73 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H2Cl2I3NO2 |
| Molecular Weight | 595.73 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 1 |
Related Iohexol Standards
- Iohexol Impurity 52 (CAS CATO-C4X-166452)
- Iohexol EP Impurity H (4,6-diiodo Isomer) (Mixture of Diastereomers) (CAS 1651211-79-8)
- Iohexol EP Impurity F (CAS 1215856-35-1)
- Iohexol Impurity 29 (CAS CATO-C4X-166429)
- Iohexol Impurity 32 (CAS CATO-C4X-166432)
- Iohexol Impurity 33 (CAS CATO-C4X-166433)
- Iohexol Impurity G (2,4-diiodo Isomer) (CAS CATO-C4X-166422)
- Iohexol EP Impurity K (CAS 35453-19-1)
Recommended Standards
- rel-Ethyl (4R,5R)-1-benzyl-5-(4-(benzylamino)phenyl)-2-(4-methoxyphenyl)-4-phenyl-4,5-dihydro-1H-imidazole-4-carboxylate (CAS 1446350-60-2)
- Ensifentrine impurity 15 (CAS CATO-C4X-335315)
- Ethyl 5-(((2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)phenyl)sulfonamido)methyl)furan-2-carboxylate (CAS 1416153-62-2)
- Biotin-PEG8-alcohol (CAS 2182601-20-1)
- Naproxen Impurity 40 (CAS 36815-04-0)
- Bortezomib Impurity 35 (CAS 1104011-35-9)
- Lopinavir EP Impurity N (CAS CATO-C4X-168214)
- Morusin (CAS 62596-29-6)
- butyl(methyl)sulfamoyl chloride (CAS 41483-74-3)
- 5-(3-Chloropropyl)imidazolidine-2,4-dione (CAS 438492-29-6)
- 2,2-Dimethyl-3-phenylcyclopropane-1-carboxylic acid (CAS 50672-13-4)
- 1-(4-Cyanobenzenesulfonyl)piperidine-4-carboxylic acid (CAS 871478-84-1)
- 1-(6-Vinylpyridin-3-yl)ethanone (CAS 1259929-69-5)
- Semaglutide impurity 103 (CAS 1446013-07-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com