Iohexol Impurity 52 CAS CATO-C4X-166452
| CAS No. | CATO-C4X-166452 |
| Molecular Formula | C11H13I3N2O3 |
| Molecular Weight | 601.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Iohexol Impurity 52.
As a process- or degradation-related impurity, Iohexol Impurity 52 (CAS CATO-C4X-166452, C11H13I3N2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Iohexol Impurity 52 (C11H13I3N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 601.95 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Iohexol Impurity 52 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13I3N2O3 |
| Molecular Weight | 601.95 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Iohexol Standards
- Iohexol EP Impurity L (CAS 37441-29-5)
- Iohexol Impurity 32 (CAS CATO-C4X-166432)
- Iohexol Impurity 33 (CAS CATO-C4X-166433)
- Iohexol EP Impurity H (4,6-diiodo Isomer) (Mixture of Diastereomers) (CAS 1651211-79-8)
- Iohexol Impurity G (2,4-diiodo Isomer) (CAS CATO-C4X-166422)
- Iohexol EP Impurity F (CAS 1215856-35-1)
- Iohexol Impurity 29 (CAS CATO-C4X-166429)
- Iohexol EP Impurity K (CAS 35453-19-1)
Recommended Standards
- Orlistat impurity 33 (CAS CATO-C4X-149933)
- Triundecanoin-d5 (CAS CATO-C4X-217150)
- Ioxaglic acid impurity A CRS (CAS 22871-58-5)
- 1,3-17:0 D5DG (CAS 1246523-65-8)
- Resmetirom impurity 136 (CAS CATO-C4X-2912136)
- Difenidol Impurity 8 HCl (CAS 17874-62-3)
- Apremilast Impurity 80 (CAS 60758-86-3)
- N-[(2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene)methyl]glycine (CAS 446830-14-4)
- CMP-Sialic acid sodium salt (CAS 1007117-62-5)
- 5-bromo-3,6-dihydro-2H-pyran-3-ol (CAS 2247401-67-6)
- 2-(2-FLUOROPHENYL)ACETAMIDE 2-(2-FLUOROPHENYL)ACETIC ACID 2-Fluorophenylacetic acid 451-82-1 AS00497 LABOTEST-BB LT00455080 O-FLUOROPHENYLACETIC ACID OTAVA-BB 7020330565 RARECHEM AL BO 0110 (CAS 451-82-1)
- 2-Amino-3-(pyridin-3-yl)propanoic acid hydrochloride (CAS 856570-92-8)
- 5-((3,5-Dichlorophenyl)amino)-4-(hydroxymethyl)-2H-pyrrol-2-one (CAS 61610-42-2)
- D-β-Asp9-Tirzepatide (CAS CATO-CPTD788932)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com