Galantamine Impurity 4 CAS 3891-74-5
| CAS No. | 3891-74-5 |
| Molecular Formula | C18H24NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 429.29 g/mol gives Galantamine Impurity 4 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Galantamine Impurity 4 (CAS 3891-74-5), a pharmacopoeial impurity reference standard (molecular formula C18H24NO3I, MW 429.29 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Galantamine Impurity 4 (C18H24NO3I) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Galantamine Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H24NO3 I |
| Molecular Weight | 429.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Galantamine Standards
- Galantamine-d6 (CAS 1128109-00-1)
- Galantamine EP Impurity E HBr (CAS 1201809-28-0)
- Galantamine EP Impurity F HBr (CAS 1556014-63-1)
- Galantamine EP Impurity B (CAS 1668-85-5)
- Galantamine Hydrobromide Racemic (CAS 193146-85-9)
- Galantamine hydrobromide (CAS 1953-04-4)
- Galantamine Impurity 5 (CAS 199014-26-1)
- Galantamine Impurity 11 (CAS 21041-10-1)
Recommended Standards
- Lovastatin Impurity 25 (CAS CATO-C4X-168425)
- Lapatinib Impurity 7 (CAS 320337-46-0)
- Tofacitinib Impurity 6 (CAS 477600-74-1)
- Methyl (R)-1-(2-bromoallyl)piperidine-2-carboxylate (CAS 1568079-65-1)
- 4-(4-Methoxy-phenyl)-[1,2,3]thiadiazole-5-carboxylic acid (CAS 340260-31-3)
- N-(bicyclo[2.2.1]Heptan-2-ylmethyl)propan-2-amine (CAS 22441-70-9)
- Methyl 4-oxo-1,4-dihydrocinnoline-6-carboxylate (CAS 876516-53-9)
- (4-Fluorophenyl)(thiophen-2-yl)methanamine hydrochloride (CAS 2126179-15-3)
- 4-Chlorothieno[2,3-d]pyrimidine-6-sulfonamide (CAS 1342732-53-9)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com