Tofacitinib Impurity 6 CAS 477600-74-1

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.477600-74-1
Molecular FormulaC13H19N5
Molecular Weight245.32 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Tofacitinib Impurity 6 CAS 477600-74-1 chemical structure

Description

CATO supplies Tofacitinib Impurity 6 (CAS 477600-74-1), a pharmacopoeial impurity reference standard (molecular formula C13H19N5, MW 245.32 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C13H19N5, Tofacitinib Impurity 6 contains a nitrogen-containing heterocyclic scaffold, a nitrile group; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 245.32 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Tofacitinib Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H19N5
Molecular Weight245.32 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms5

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