6-beta-Methyl Fluorometholone CAS 3918-13-6
| CAS No. | 3918-13-6 |
| Molecular Formula | C22H29FO4 |
| Molecular Weight | 376.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-beta-Methyl Fluorometholone (CAS 3918-13-6), molecular formula C22H29FO4 and molecular weight 376.46 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, 6-beta-Methyl Fluorometholone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 376.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-beta-Methyl Fluorometholone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H29FO4 |
| Molecular Weight | 376.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
Recommended Standards
- Betamethasone Valerate EP Impurity B (CAS 1879-77-2)
- Fluorometholone D Homo Derivative (CAS CATO-C4X-19339)
- Betamethasone Impurity 125 (CAS CATO-C4X-1437125)
- Fluocortolone Pivalate EP Impurity A (CAS 152-97-6)
- Methyl 2-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxylate (CAS 1506052-39-6)
- (S)-N1-((1-Benzylpyrrolidin-2-yl)methyl)-N1-methylethane-1,2-diamine (CAS 1354007-90-1)
- 4-(Chloromethyl)-3-(difluoromethyl)-5-fluoropyridin-2-amine (CAS 1805323-94-7)
- Xanthofulvin (CAS 151466-15-8)
- 1,4-Bis((1H-1,2,4-triazol-1-yl)methyl)benzene (CAS 143131-66-2)
- Fasudil Impurity 14 (CAS CATO-C4X-136514)
- 3-Chloro-2-fluoro-4-nitrophenol (CAS 1805115-08-5)
- Sulfo-Succinimidyl-4-hydroxybenzoate (CAS 223593-91-7)
- 4-Bromo-3-ethoxybenzoic acid ethyl ester (CAS 220380-11-0)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
Why CATO?
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