Dexamethasone Acetate EP Impurity I CAS 3949-26-6
| CAS No. | 3949-26-6 |
| Molecular Formula | C26H33FO7 |
| Molecular Weight | 476.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Dexamethasone Acetate EP Impurity I (CAS 3949-26-6), a pharmacopoeial impurity reference standard (molecular formula C26H33FO7, MW 476.53 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C26H33FO7, Dexamethasone Acetate EP Impurity I contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 476.53 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Dexamethasone Acetate EP Impurity I under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H33FO7 |
| Molecular Weight | 476.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone Impurity 121 (CAS 2600-31-9)
- Dexamethasone 21-Phosphate D5 (CAS 312-93-6 (unlabelled))
- Dexamethasone Sodium Phosphate EP Impurity H (CAS 162968-22-1)
- Dexamethasone impurity 93 (CAS 2414-45-1)
- Dexamethasone Impurity 108 (CAS CATO-C4X-1165108)
- Dexamethasone Impurity 109 (CAS CATO-C4X-1165109)
- Dexamethasone Impurity 117 (CAS CATO-C4X-1165117)
- Dexamethasone Impurity 128 (CAS CATO-C4X-1165128)
Recommended Standards
- Palbociclib Impurity 146 (CAS 2955712-44-2)
- Triamcinolone Acetonide EP Impurity F (CAS 3870-07-3)
- Palbociclib impurity 130 (CAS CATO-C4X-1125130)
- Betamethasone Acetate EP Impurity C (CAS 330157-05-6)
- Tadalafil Impurity 136 (CAS 52302-45-1)
- Paliperidone Impurity 3 (CAS CATO-C4X-17243)
- Docetaxel Impurity 25 (CAS CATO-C4X-161925)
- (4s)-4-Amino-3,4-dihydro-2h-1lambda6-benzothiopyran-1,1-dione hydrochloride (CAS 1423040-73-6)
- [2,4'-bipyridine]-3-carbonitrile (CAS 870065-16-0)
- 4-((9H-Fluoren-3-yl)amino)-4-oxobut-2-enoic acid (CAS 6296-24-8)
- Febuxostat Impurity 56 (CAS CATO-C4X-116256)
- 5-(trifluoromethyl)-2,3-dihydro-1H-isoindol-1-one (CAS 1261590-26-4)
- 5-Fluoro-4-methoxy-2-nitroaniline (CAS 446-20-8)
- Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 330456-24-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com