Dexamethasone Impurity 128 CAS CATO-C4X-1165128
| CAS No. | CATO-C4X-1165128 |
| Molecular Formula | C22H30FO8P |
| Molecular Weight | 472.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dexamethasone Impurity 128 (CAS CATO-C4X-1165128) is a certified pharmaceutical impurity reference standard with the molecular formula C22H30FO8P and a molecular weight of 472.44 g/mol.
The molecular framework of Dexamethasone Impurity 128 (C22H30FO8P) is characterized by a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Dexamethasone Impurity 128 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H30FO8P |
| Molecular Weight | 472.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone Impurity 108 (CAS CATO-C4X-1165108)
- Dexamethasone Impurity 109 (CAS CATO-C4X-1165109)
- Dexamethasone Impurity 117 (CAS CATO-C4X-1165117)
- Dexamethasone Sodium Phosphate EP Impurity C (CAS CATO-C4X-116522)
- Dexamethasone Sodium Phosphate Impurity B (CAS 360-63-4)
- Dexamethasone Sodium Phosphate EP Impurity D (CAS CATO-C4X-116528)
- Dexamethasone Sodium Phosphate EP Impurity E (CAS CATO-C4X-116529)
- Dexamethasone Sodium Phosphate EP Impurity F (CAS CATO-C4X-116530)
Recommended Standards
- 4-Nitrophenyl 2-acetamido-3-O-acetyl-4-6-O-benzylidene-2-deoxy-α-D-glucopyranoside (CAS 23262-56-8)
- 2-((5-Cyano-4-(trifluoromethyl)-[2,4'-bipyridin]-6-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (CAS 625378-14-5)
- Sibirioside A (CAS 173046-19-0)
- Dexamethasone Phosphate (CAS 312-93-6)
- N-Nitroso Meropenem Impurity A (CAS CATO-C4X-130966)
- Apremilast Impurity N9 (CAS 67614-42-0)
- Relugolix Impurity 111 (CAS CATO-C4X-2429111)
- 1,2-Bis(3,4-dicyanophenoxy)-4-tert-butylbenzene (CAS 99276-81-0)
- 4-[(2-Chlorophenyl)methyl]piperidin-4-ol (CAS 1225734-21-3)
- Eliglustat Impurity 7 (CAS 491833-28-4)
- 2-Bromo-5-(trifluoromethyl)pyridine-4-acetonitrile (CAS 1227572-97-5)
- 5-Amino-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 41740-43-6)
- 1-(Bromomethyl)-1-(2-methoxyethoxy)cycloheptane (CAS 1247553-28-1)
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com