Nifedipine EP Impurity C CAS 39562-27-1
| CAS No. | 39562-27-1 |
| Molecular Formula | C12H11NO5 |
| Molecular Weight | 249.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Nifedipine EP Impurity C meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Nifedipine EP Impurity C (CAS 39562-27-1), a pharmacopoeial impurity reference standard (molecular formula C12H11NO5, MW 249.22 g/mol) used for the identification and quantification of trace impurities in APIs.
Nifedipine EP Impurity C (C12H11NO5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H11NO5 |
| Molecular Weight | 249.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Nitrogen Atoms | 1 |
Related Nifedipine Standards
- Nifedipine EP Impurity C (E-Isomer) (CAS 111304-29-1)
- Nifedipine EP Impurity C (Z-Isomer) (CAS 111304-31-5)
- Nifedipine Impurity 22 (CAS CATO-C4X-141022)
- Nifedipine Impurity 35 (CAS CATO-C4X-141035)
- Nifedipine Impurity 40 (CAS 464917-82-6)
- Nifedipine Impurity 36 (CAS CATO-C4X-141036)
- Nifedipine Impurity 23 (CAS 65962-15-4)
- Nifedipine Impurity 34 (CAS 89088-71-1)
Recommended Standards
- Mizoribine Impurity 3 (CAS 91738-15-7)
- Lercanidipine Impurity 64（Z-Isomer） (CAS 119128-13-1)
- Nintedanib Impurity 31 (CAS 2514952-69-1)
- Lercanidipine Impurity 47 （Z-Isomer） (CAS CATO-C4X-136447)
- Sildenafil Impurity 84 (CAS CATO-C4X-112884)
- Lurasidone Impurity 52 (CAS 1807983-63-6)
- Finasteride Impurity 52 (CAS CATO-C4X-164552)
- Aprocitentan impurity 1 (CAS CATO-C4X-33551)
- Biphenyl-3,4’-dicarboxylic acid (CAS 92152-01-7)
- 2-(2-Bromoacetyl)-5-methylisoxazol-3(2H)-one (CAS 38100-61-7)
- Terbutaline Impurity 44 (CAS 2095852-55-2)
- 2-Amino-6-methoxypyridine-3,5-dicarbonitrile (CAS 36926-81-5)
- 4-(4-Bromophenyl)-2-methylnicotinonitrile (CAS 881423-31-0)
- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com