Nifedipine Impurity 23 CAS 65962-15-4
| CAS No. | 65962-15-4 |
| Molecular Formula | C7H5Br2NO2 |
| Molecular Weight | 294.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Nifedipine Impurity 23 (CAS 65962-15-4, C7H5Br2NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system, Nifedipine Impurity 23 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 294.93 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Nifedipine Impurity 23 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5Br2NO2 |
| Molecular Weight | 294.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Nifedipine Standards
- Nifedipine Impurity 36 (CAS CATO-C4X-141036)
- Nifedipine Impurity 29 (CAS CATO-C4X-141029)
- Nifedipine EP Impurity B (CAS 50428-14-3)
- Nifedipine Impurity 25 (CAS 73372-63-1)
- Nifedipine Impurity 10 (CAS 114709-68-1)
- Nifedipine Impurity 8 (CAS 74936-71-3)
- Nifedipine Impurity 22 (CAS CATO-C4X-141022)
- Nifedipine EP Impurity C (E-Isomer) (CAS 111304-29-1)
Recommended Standards
- Ambroxol Impurity 20 (CAS 609-85-8)
- 4-Bromo-6,7-dichloro-8-fluoroquinoline (CAS 1375302-37-6)
- 4-BROMO-1-(BROMOMETHYL)-2-NITROBENZENE 4-BROMO-2-NITROBENZYL BROMIDE 5-BROMO-2-(BROMOMETHYL)NITROBENZENE 82420-34-6 BC005089 (CAS 82420-34-6)
- 3-Bromo-2,4-dichloro-8-fluoroquinoline (CAS 1447959-10-5)
- Ozanimod impurity 35 (CAS 1306760-61-1)
- Revefenacin impurity 75 (CAS CATO-C4X-203175)
- Irbesartan Impurity 44 (CAS CATO-C4X-166644)
- (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-ol (CAS 81794-12-9)
- Atenolol EP Impurity A (CAS 17194-82-0)
- 3,8-Di(but-2-en-1-yl)-1,7-dimethyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione (CAS 915880-05-6)
- 2-(2-(2-Fluorophenoxy)ethyl)-1,3-dioxane (CAS 1443305-81-4)
- (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid sulfuric acid salt (CAS 21881-27-6)
- Benzyl 2-(3,3-difluorocyclohexyl)-4-phenylpiperidine-1-carboxylate (CAS 1241505-07-6)
- Lixisenatide (CAS 320367-13-3（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com