3'-(Trifluoromethyl)[1,1'-biphenyl]-4-amine CAS 397-28-4
| CAS No. | 397-28-4 |
| Molecular Formula | C13H10F3N |
| Molecular Weight | 237.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3'-(Trifluoromethyl)[1,1'-biphenyl]-4-amine (C13H10F3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 3'-(Trifluoromethyl)[1,1'-biphenyl]-4-amine (CAS 397-28-4), a certified reference material (molecular formula C13H10F3N, MW 237.22 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3'-(Trifluoromethyl)[1,1'-biphenyl]-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10F3N |
| Molecular Weight | 237.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 2-((1-Ethyl-3-(trifluoromethyl)-1h-pyrazol-5-yl)methoxy)ethan-1-amine (CAS 1170513-11-7)
- 6-(Trifluoromethyl)-[1,1'-biphenyl]-3-amine (CAS 1214341-39-5)
- 4-(2-Methyl-3-(trifluoromethyl)phenyl)pyridine (CAS 1214378-20-7)
- 2-Methyl-4-(4-(trifluoromethyl)phenyl)pyridine (CAS 1261635-94-2)
- 2-methyl-6-[3-(trifluoromethyl)phenyl]pyridine (CAS 1261758-54-6)
- 4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-amine (CAS 189575-70-0)
- 5-(Trifluoromethyl)-9-oxa-2-azaspiro[5.5]undecan-3-one (CAS 1909308-87-7)
- 2-(Trifluoromethyl)[1,1-biphenyl]-2-amine (CAS 438-84-6)
Recommended Standards
- 3'-(Trifluoromethyl)-[1,1'-biphenyl]-2-amine (CAS 365-06-0)
- 3-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine (CAS 449-42-3)
- 2-amino-7-(trifluoromethyl)-3,4-dihydroquinazolin-4-one (CAS 50440-86-3)
- 3-(Trifluoromethyl)-3,3a,4,5,6,7,8,9-octahydrocycloocta[c]isoxazol-3-ol (CAS 918418-94-7)
- 1,7-Hexadecadiene (CAS 125110-62-5)
- 2-((4-Bromothiophen-2-yl)(methyl)amino)acetic acid (CAS 1248441-81-7)
- N-(5-Methyl-1,2-oxazol-3-yl)-2-(pyridin-2-ylsulfanyl)acetamide (CAS 297149-96-3)
- (S)-1-(4-Chloro-3-methylphenyl)ethanamine hydrochloride (CAS 1624272-56-5)
- (E)-3-(Pyridin-3-yl)prop-2-en-1-ol (CAS 120277-39-6)
- 2-((2-Cyclobutylthiazol-4-yl)methoxy)aniline (CAS 1707734-82-4)
- Ethyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 187035-79-6)
- 4-Bromo-6-chloro-7-fluoro-1H-indole (CAS 2369752-82-7)
- 2-(4-(Difluoromethyl)-2-iodo-5-(trifluoromethoxy)pyridin-3-yl)acetonitrile (CAS 1804764-20-2)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
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