Fluticasone Furoate 11-Keto Impurity CAS 397864-56-1
| CAS No. | 397864-56-1 |
| Molecular Formula | C27H27F3O6S |
| Molecular Weight | 536.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Fluticasone Furoate 11-Keto Impurity meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Fluticasone Furoate 11-Keto Impurity (CAS 397864-56-1), a pharmacopoeial impurity reference standard (molecular formula C27H27F3O6S, MW 536.56 g/mol) used for the identification and quantification of trace impurities in APIs.
Fluticasone Furoate 11-Keto Impurity (C27H27F3O6S) contains a steroid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C27H27F3O6S |
| Molecular Weight | 536.56 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fluticasone Standards
- Fluticasone Impurity 35 (CAS CATO-C4X-165035)
- Fluticasone Furoate (CAS 397864-44-7)
- Fluticasone Furoate EP Impurity I (CAS 3086156-07-9)
- Fluticasone Impurity 104 (CAS CATO-C4X-1650104)
- Fluticasone Furoate EP Impurity F (CAS CATO-C4X-165023)
- Fluticasone Impurity N3 (CAS 398454-98-3)
- Fluticasone Furoate D3 (CAS 397864-44-7(unlabelled))
- Fluticasone Impurity 75 (CAS CATO-C4X-165075)
Recommended Standards
- 5-Amino-6-chloro-2-phenylpyridazin-3(2H)-one (CAS 1698-59-5)
- 2-(Benzo[d][1,3]dioxol-5-yl)-N-(4-methoxybenzyl)-3-(4-methoxyphenyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide (CAS 1023415-57-7)
- 1-{(2S)-1-[(11bS)-2,6-Dimethyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yloxy]propan-2-yl}-3-phenylurea (CAS 1357562-63-0)
- (R)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-bis(4-nitrophenyl)-[1,1'-binaphthalene]-2,2'-diol (CAS 791616-67-6)
- Relugolix Impurity 35 (CAS CATO-C4X-242935)
- Fluticasone Furoate Impurity 6 (CAS CATO-C4X-32546)
- Pitavastatin Impurity 111 (CAS CATO-C4X-1037111)
- 3-(Benzofuran-2-yl)-6-ethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole (CAS 1713714-61-4)
- 1,1'-Di-tert-butyl-4'-hydroxy-[3,4'-bipiperidin]-4-one (CAS 2101206-63-5)
- (S)-3-Amino-2-(4-bromo-phenyl)-propan-1-ol hydrochloride (CAS 1442114-60-4)
- 3-Chloro-1-methyl-1H-pyrazol-4-ol (CAS 2685800-18-2)
- 1,1-Difluoro-6-(2-hydroxyphenyl)hex-5-ene-2,4-dione (CAS 941866-58-6)
- 2-(4-Bromo-phenyl)-4-chloro-7-fluoro-quinazoline (CAS 885277-86-1)
- Casein Kinase II Receptor Peptide (CAS 198481-81-1)
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