Fluticasone Impurity 35 CAS CATO-C4X-165035
| CAS No. | CATO-C4X-165035 |
| Molecular Formula | C27H28F2O7S |
| Molecular Weight | 534.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Fluticasone Impurity 35 (CAS CATO-C4X-165035) is a certified pharmaceutical impurity reference standard with the molecular formula C27H28F2O7S and a molecular weight of 534.57 g/mol.
Fluticasone Impurity 35 (C27H28F2O7S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H28F2O7S |
| Molecular Weight | 534.57 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fluticasone Standards
- Fluticasone Furoate 11-Keto Impurity (CAS 397864-56-1)
- Fluticasone Furoate EP Impurity F (CAS CATO-C4X-165023)
- Fluticasone Furoate (CAS 397864-44-7)
- Fluticasone Furoate EP Impurity I (CAS 3086156-07-9)
- Fluticasone Impurity 104 (CAS CATO-C4X-1650104)
- Fluticasone Impurity N3 (CAS 398454-98-3)
- Fluticasone Furoate D3 (CAS 397864-44-7(unlabelled))
- Fluticasone Furoate Impurity 1 (CAS CATO-C4X-32541)
Recommended Standards
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- Dabrafenib Impurity 19 (CAS 1907654-22-1)
- Sulindac EP Impurity D (CAS 134439-52-4)
- Imidafenacin Impurity 6 (CAS 503598-40-1)
- Flurbiprofen Impurity 127 (CAS CATO-C4X-1444127)
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