Coclaurine Impurity 1 CAS 4078-65-3
| CAS No. | 4078-65-3 |
| Molecular Formula | C19H23NO4 |
| Molecular Weight | 329.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C19H23NO4, Coclaurine Impurity 1 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 329.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Coclaurine Impurity 1 (CAS 4078-65-3), a pharmacopoeial impurity reference standard (molecular formula C19H23NO4, MW 329.39 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H23NO4 |
| Molecular Weight | 329.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Coclaurine Standards
- Coclaurine Impurity 16 (CAS CATO-C4X-27516)
- Coclaurine Impurity 6 (CAS 3472-22-8)
- Coclaurine Impurity 113 (CAS 2158198-78-6(TFA Salt))
- Coclaurine Impurity 114 (CAS 31804-74-7)
- Coclaurine Impurity 115 (CAS CATO-C4X-275115)
- Coclaurine Impurity 15 (CAS CATO-C4X-27515)
- (+)-Coclaurine (CAS 2196-60-3)
- Coclaurine (CAS 486-39-5)
Recommended Standards
- Labetalol EP Impurity A (CAS 1391051-99-2)
- Sinomenine (CAS 115-53-7)
- Fenoterol Impurity 6 (CAS CATO-C4X-20776)
- Boc-D-Glu(OcHex)-OH (CAS 133464-27-4)
- Sarpogrelate Impurity 13 (CAS CATO-C4X-291313)
- Arotinolol impurity 25 (CAS 96991-65-0)
- LCZ-696 Impurity 57 (CAS 149709-58-0)
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Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com