Lenvatinib Impurity 134 CAS 417723-66-1

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.417723-66-1
Molecular FormulaC13H13ClN2O2
Molecular Weight264.71 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Lenvatinib Impurity 134 CAS 417723-66-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 264.71 g/mol gives Lenvatinib Impurity 134 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Lenvatinib Impurity 134 (CAS 417723-66-1) is a certified pharmaceutical impurity reference standard with the molecular formula C13H13ClN2O2 and a molecular weight of 264.71 g/mol.

Based on its molecular formula C13H13ClN2O2, Lenvatinib Impurity 134 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 264.71 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Lenvatinib Impurity 134 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H13ClN2O2
Molecular Weight264.71 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2

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