Lenvatinib Impurity 178 CAS CATO-C4X-1140178
| CAS No. | CATO-C4X-1140178 |
| Molecular Formula | C14H15NO4 |
| Molecular Weight | 261.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Lenvatinib Impurity 178 (CAS CATO-C4X-1140178, C14H15NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lenvatinib Impurity 178 (C14H15NO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Lenvatinib Impurity 178 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H15NO4 |
| Molecular Weight | 261.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Lenvatinib Standards
- Lenvatinib Impurity 165 (CAS CATO-C4X-1140165)
- Lenvatinib Impurity 15 (CAS 796848-80-1)
- Lenvatinib Impurity 134 (CAS 417723-66-1)
- Lenvatinib Impurity 109 (CAS 2852-69-9)
- Lenvatinib Impurity 160 (CAS CATO-C4X-1140160)
- Lenvatinib Impurity 82 (CAS CATO-C4X-114082)
- Lenvatinib Impurity 74 (CAS CATO-C4X-114074)
- Lenvatinib Impurity 140 (CAS CATO-C4X-1140140)
Recommended Standards
- Arbidol Impurity 49 (CAS 20862-91-3)
- Sodium Valproate Impurity 23 (CAS 4443-26-9)
- CAS 501921-23-9 (CAS 501921-23-9)
- Levocarnitine impurity 28 (CAS 256928-74-2)
- Empagliflozin Impurity 12 (CAS 1620758-34-0 & 2452301-18-5)
- Ribavirin Impurity 58 (CAS 659722-55-1)
- Lufenuron EP Impurity G (CAS CATO-C4X-28873)
- 5-Hydroxy-3-(4-pyridyl)isoxazole (CAS 89819-63-6)
- 1-Ethyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 155377-11-0)
- Ethyl 2-(benzyloxy)-4-(trifluoromethyl)benzoate (CAS 1823511-40-5)
- 2-(2-Azidoethoxy)-4-methoxybenzoic acid (CAS 2104152-60-3)
- rel-(3R,5S)-Benzyl 3,5-difluoropiperidine-1-carboxylate (CAS 259110-56-0)
- 5-Bromo-2-(1-isopropylpiperidin-3-yl)pyridine hydrochloride (CAS 1361116-88-2)
- [His]1-Acetylated Semaglutide (CAS CATO-C4X-2226219)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com