Clonidine Hydrochloride CAS 4205-91-8
| CAS No. | 4205-91-8 |
| Molecular Formula | C9H9Cl2N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Clonidine Hydrochloride (CAS 4205-91-8), a certified reference material (molecular formula C9H9Cl2N3HCl, MW 266.55 g/mol) for analytical method development and quality control.
The molecular framework of Clonidine Hydrochloride (C9H9Cl2N3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Clonidine Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9Cl2N3 HCl |
| Molecular Weight | 266.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Clonidine Standards
- Clonidine Impurity 2 (CAS 10113-35-6)
- Clonidine Impurity 8 (CAS 148950-50-9)
- Clonidine Impurity 1 (CAS 21709-18-2)
- Clonidine Impurity 3 (CAS 27806-81-1)
- Clonidine Impurity 5 (CAS 39075-78-0)
- Clonidine (CAS 4205-90-7)
- Clonidine Hydrochloride EP Impurity A (CAS 5391-39-9)
- Clonidine EP Impurity B (CAS 54707-71-0)
Recommended Standards
- 4-Ethoxy-N-[2-(hydrazinecarbonyl)phenyl]benzene-1-sulfonamide (CAS 380342-12-1)
- (S)-3-Amino-1-methylpyrrolidine (CAS 214357-95-6)
- Thiazole-4-carboxylic acid hydrobromide (CAS 3973-07-7)
- 2,4-Dibromo-5-methylaniline (CAS 67643-51-0)
- Ribociclib Impurity 20 (CAS CATO-C4X-310020)
- Methyl cis-9,10-Methyleneoctadecenoate (CAS 3220-60-8)
- Ac-Thr-OMe (CAS 2458-78-8)
- (3aS,7aS)-Hexahydroisobenzofuran-1,3-dione (CAS 31982-85-1)
- 3-(4-Chlorophenyl)-1-(p-tolyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-35-5)
- Fibronectin Adhesion-Promoting Peptide (CAS 125720-21-0)
Why CATO?
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