N-(3-Chloro-4-methoxyphenyl)-4-fluorobenzamide CAS 423735-68-6
| CAS No. | 423735-68-6 |
| Molecular Formula | C14H11ClFNO2 |
| Molecular Weight | 279.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-(3-Chloro-4-methoxyphenyl)-4-fluorobenzamide (CAS 423735-68-6) is a high-purity analytical reference standard with the molecular formula C14H11ClFNO2 and a molecular weight of 279.69 g/mol.
N-(3-Chloro-4-methoxyphenyl)-4-fluorobenzamide (C14H11ClFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11ClFNO2 |
| Molecular Weight | 279.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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- 2-(Aminomethyl)-3,6-diamino-5-(difluoromethyl)pyridine (CAS 1804443-71-7)
- 2-Fluoro-4-(propan-2-yl)benzoic acid (CAS 1341179-82-5)
- Tau Peptide (45-73) (Exon 2/Insert 1 Domain) trifluoroacetate salt (CAS 2022956-54-1)
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