N-(4-Chloro-2-fluorophenyl)-4-methoxybenzamide CAS 546096-46-2

Purity 97%+In StockPharmaceutical Standards
CAS No.546096-46-2
Molecular FormulaC14H11ClFNO2
Molecular Weight279.69 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-Chloro-2-fluorophenyl)-4-methoxybenzamide CAS 546096-46-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 279.69 g/mol gives N-(4-Chloro-2-fluorophenyl)-4-methoxybenzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

N-(4-Chloro-2-fluorophenyl)-4-methoxybenzamide (CAS 546096-46-2), molecular formula C14H11ClFNO2 and molecular weight 279.69 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, N-(4-Chloro-2-fluorophenyl)-4-methoxybenzamide (C14H11ClFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 279.69 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(4-Chloro-2-fluorophenyl)-4-methoxybenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H11ClFNO2
Molecular Weight279.69 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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