Flurbiprofen Impurity 1 CAS 42771-81-3
| CAS No. | 42771-81-3 |
| Molecular Formula | C20H21FO4 |
| Molecular Weight | 344.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Flurbiprofen Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Flurbiprofen Impurity 1 (CAS 42771-81-3), a pharmacopoeial impurity reference standard (molecular formula C20H21FO4, MW 344.38 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Flurbiprofen Impurity 1 (C20H21FO4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H21FO4 |
| Molecular Weight | 344.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | F-containing |
Related Flurbiprofen Standards
- Flurbiprofen Impurity 14 (CAS CATO-C4X-144414)
- Flurbiprofen Impurity 29 (CAS 1206101-29-2)
- Flurbiprofen Impurity 81 (CAS CATO-C4X-144481)
- Flurbiprofen Impurity 94 (CAS 121734-75-6)
- Flurbiprofen Impurity 128 (CAS 1515948-47-6)
- Flurbiprofen Impurity 159 (CAS 179766-28-0)
- Flurbiprofen Impurity 100 (CAS CATO-C4X-1444100)
- Flurbiprofen Impurity 151 (CAS 836607-32-0)
Recommended Standards
- Glipizide Impurity 24 (CAS CATO-C4X-140724)
- Latanoprost EP Impurity D (CAS 2088449-88-9)
- Cefdinir Impurity 72 (CAS CATO-C4X-121072)
- 7-AVCA Impurity 2 (CAS 33748-00-4)
- Amlodipine Impurity 64 (CAS 27807-84-7)
- Bumetanide EP Impurity A Na salt (CAS CATO-C4X-198698)
- Vitamin K1 Impurity 2 (CAS 15576-40-6)
- 7-Methoxy-6-methyl-1H-pyrrolo[3,4-c]pyridine-2(3H)-carboximidamide (CAS 807287-37-2)
- 2-[(6-Chloro-3-nitropyridin-2-yl)amino]-3-methylbutanoic acid (CAS 1396963-89-5)
- 3-O-a-D-Glucosyl Isomaltol (CAS 85559-61-1)
- (R)-1-(3,5-Dimethylpyridazin-4-yl)ethan-1-ol (CAS 2800226-87-1)
- (3-Hydroxypyridin-4-yl)boronic acid (CAS 2096334-63-1)
- 3-(1H-indol-3-yl)-3-(pyridin-4-yl)propanoic acid (CAS 797779-89-6)
- Heptapeptide-6 (CAS CATO-CPTD788823)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com