Flurbiprofen Impurity 81 CAS CATO-C4X-144481
| CAS No. | CATO-C4X-144481 |
| Molecular Formula | C24H16F2 |
| Molecular Weight | 342.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Flurbiprofen Impurity 81 (CAS CATO-C4X-144481, C24H16F2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Flurbiprofen Impurity 81 (C24H16F2) is characterized by fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Flurbiprofen Impurity 81 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H16F2 |
| Molecular Weight | 342.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Flurbiprofen Standards
- Flurbiprofen Impurity 29 (CAS 1206101-29-2)
- Flurbiprofen Impurity 1 (CAS 42771-81-3)
- Flurbiprofen Impurity 14 (CAS CATO-C4X-144414)
- Flurbiprofen Impurity 159 (CAS 179766-28-0)
- Flurbiprofen Impurity 100 (CAS CATO-C4X-1444100)
- Flurbiprofen Impurity 94 (CAS 121734-75-6)
- Flurbiprofen Impurity 156 (CAS CATO-C4X-1444156)
- Flurbiprofen Impurity 128 (CAS 1515948-47-6)
Recommended Standards
- Baloxavir Impurity 23 (CAS CATO-C4X-210823)
- 22697-65-0 5V53651JOR 4',5,7-Trihydroxy-3,6-dimethoxyflavone 5,7-Dihydroxy-2-(4-hydroxyphenyl)-3,6-dimethoxy-4H-1-benzopyran-4-one NSC 271638 UNII-5V53651JOR (CAS 22697-65-0)
- Baloxavir Impurity 5 (CAS CATO-C4X-21085)
- 6-tert-Butyl-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-3,4-dihydropyrimidin-4-one (CAS 478259-92-6)
- Pioglitazone Impurity 02 (CAS 101931-00-4)
- Lifitegrast Impurity 45 (CAS CATO-C4X-240945)
- Irsogladine Impurity 7 (CAS CATO-C4X-29147)
- 3-(3-azidopropoxy)-N,N-dimethylaniline (CAS 1250143-79-3)
- 4-methylthiolan-3-amine (CAS 115660-79-2)
- N-Methyl-1-(1-(2,2,2-trifluoroethyl)-1H-pyrazol-3-yl)methanamine hydrochloride (CAS 1855899-60-3)
- 2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-7-amine (CAS 1546447-84-0)
- N-((1-(methylsulfonyl)cyclopropyl)methyl)thietan-3-amine (CAS 1861784-40-8)
- 3-Iodo-1-methyl-1H-pyrrole-2-carboxylic acid (CAS 1823935-30-3)
- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
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