Dabigatran Impurity 67 CAS 429659-01-8
| CAS No. | 429659-01-8 |
| Molecular Formula | C18H20N4O5 |
| Molecular Weight | 372.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dabigatran Impurity 67.
CATO supplies Dabigatran Impurity 67 (CAS 429659-01-8), a pharmacopoeial impurity reference standard (molecular formula C18H20N4O5, MW 372.38 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C18H20N4O5, Dabigatran Impurity 67 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 372.38 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Dabigatran Impurity 67 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H20N4O5 |
| Molecular Weight | 372.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
Related Dabigatran Standards
- Dabigatran Impurity 116 (CAS CATO-C4X-1089116)
- Dabigatran Impurity 27 (CAS 1642853-67-5)
- Dabigatran Impurity 28 (CAS 1456889-80-7)
- Dabigatran Impurity 127 (CAS 1422435-37-7)
- Dabigatran Impurity 133 (CAS CATO-C4X-1089133)
- Dabigatran Impurity 100 (CAS CATO-C4X-1089100)
- Dabigatran Impurity 107 (CAS CATO-C4X-1089107)
- Dabigatran Impurity 113 (CAS CATO-C4X-1089113)
Recommended Standards
- Tert-butyl (1R,5R)-8-oxo-10-(2,2,2-trifluoroethyl)-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(4H)-carboxylate (CAS 2188182-47-8)
- Ruxolitinib Impurity 74 (CAS CATO-C4X-205874)
- PF-04217903 (CAS 956905-27-4)
- (5-fluoro-2-hydroxyphenyl)(1-phenyl-1H-pyrazol-4-yl)methanone phenylhydrazone (CAS 1006492-56-3)
- Cefdinir Impurity 33 (CAS CATO-C4X-121033)
- Fluocinolone Acetonide impurity 118 (CAS CATO-C4X-238118)
- Oclacitinib impurity 12 (CAS 1538596-97-2)
- (4-Bromo-3-phenyl-1H-pyrazol-5-yl)methanol (CAS 1240217-33-7)
- 1-Methyl-1,4,5,6-tetrahydrocyclopenta[b]pyrrole (CAS 147329-68-8)
- 6-(Aminomethyl)-3-(difluoromethyl)-4-nitropyridin-2-amine (CAS 1804717-20-1)
- 7-methoxy-1,2,3,4,9,10-hexahydroacridin-9-one (CAS 5778-47-2)
- Ethyl 2-Oxo-3-piperidinecarboxylate (CAS 3731-16-6)
- Dehydro Indapamide-d3 (CAS 1185057-48-0)
- Vasonatrin Peptide (VNP) trifluoroacetate salt (CAS 141676-35-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com