Clavulanate Potassium EP Impurity C CAS 86917-74-0
| CAS No. | 86917-74-0 |
| Molecular Formula | C10H16N2O2 |
| Molecular Weight | 196.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Clavulanate Potassium EP Impurity C (CAS 86917-74-0), a pharmacopoeial impurity reference standard (molecular formula C10H16N2O2, MW 196.25 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Clavulanate Potassium EP Impurity C (C10H16N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H16N2O2 |
| Molecular Weight | 196.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 2 |
Related Clavulanate Standards
- Potassium Clavulanate impurity 25 (CAS 128173-47-7)
- Potassium Clavulanate impurity 23 (CAS 112240-59-2)
- Clavulanate Potassium EP Impurity A (CAS 4744-51-8)
- Potassium Clavulanate impurity 22 (CAS 148601-26-7)
- Potassium Clavulanate EP Impurity M (CAS 3033-62-3)
- Clavulanate Potassium EP Impurity D (CAS 404839-11-8)
- Potassium Clavulanate Impurity 21 (CAS CATO-C4X-114621)
- Clavulanate Potassium EP Impurity B (CAS 96681-85-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com