Sildenafil Impurity 54 CAS 133261-07-1
| CAS No. | 133261-07-1 |
| Molecular Formula | C10H16N2O2 |
| Molecular Weight | 196.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sildenafil Impurity 54 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Sildenafil Impurity 54 (CAS 133261-07-1), a pharmacopoeial impurity reference standard (molecular formula C10H16N2O2, MW 196.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Sildenafil Impurity 54 (C10H16N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C10H16N2O2 |
| Molecular Weight | 196.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 2 |
Related Sildenafil Standards
- Sildenafil Impurity 21 (CAS 268204-00-8)
- Sildenafil Impurity 30 (CAS 59259-90-4)
- Sildenafil Impurity 99 (CAS CATO-C4X-112899)
- Sildenafil Impurity 253 (CAS CATO-C4X-1128253)
- Sildenafil Impurity 45 (CAS 62871-12-9)
- Sildenafil Impurity 1 (CAS 42926-52-3)
- Sildenafil Impurity 56 (CAS CATO-C4X-112856)
- Sildenafil Impurity 274 (CAS 1358966-40-1)
Recommended Standards
- Clavulanate Potassium EP Impurity C (CAS 86917-74-0)
- Vildagliptin Impurity 19 (CAS 243145-00-8)
- Carvedilol Impurity 24 (CAS 42988-85-2)
- Benzophenone Hydrazone (CAS 5350-57-2)
- Olodaterol Impurity 15 (CAS CATO-C4X-194315)
- Rivastigmine Impurity 26 (CAS 1213234-40-2)
- Dasatinib Impurity 26 (CAS CATO-C4X-160726)
- Dexmedetomidine impurity 63 (CAS 32917-52-5)
- tert-Butyl (4,5-dibromothiophen-2-yl)carbamate (CAS 943321-93-5)
- (Furan-2-yl(hydroxy)methyl)diphenylphosphine oxide (CAS 371958-83-7)
- Oxymorphone Hydrochloride Monohydrate (CAS 1033330-03-8)
- N-((6-Methoxypyridin-3-yl)methyl)tetrazolo[1,5-b]pyridazin-6-amine (CAS 931041-79-1)
- (S)-3-(Pyrrolidin-2-yl)pyridine dihydrochloride (CAS 287966-92-1)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com