7-{2-[(4-chlorophenyl)methoxy]phenyl}pyrazolo[1,5-a]pyrimidine-3-carbonitrile CAS 439109-61-2
| CAS No. | 439109-61-2 |
| Molecular Formula | C20H13ClN4O |
| Molecular Weight | 360.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 7-{2-[(4-chlorophenyl)methoxy]phenyl}pyrazolo[1,5-a]pyrimidine-3-carbonitrile (C20H13ClN4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
7-{2-[(4-chlorophenyl)methoxy]phenyl}pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 439109-61-2), molecular formula C20H13ClN4O and molecular weight 360.80 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-{2-[(4-chlorophenyl)methoxy]phenyl}pyrazolo[1,5-a]pyrimidine-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H13ClN4O |
| Molecular Weight | 360.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related chlorophenyl Standards
- 4-(4-Chlorophenyl)-1-{5H-pyrimido[5,4-b]indol-4-yl}-1H-pyrazol-3-amine (CAS 318469-18-0)
- 1-(2-Chlorophenyl)-3-((5-(furan-2-carbonyl)thiophen-2-yl)methyl)urea (CAS 1798022-45-3)
- Ethyl 2-(1-((2-chlorophenyl)sulfonyl)-3-oxopiperazin-2-yl)acetate (CAS 318288-72-1)
- Methyl 2-((3-(4-chlorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate (CAS 28831-26-7)
- 2-{[3-(4-chlorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]sulfanyl}acetohydrazide (CAS 133764-45-1)
- 2-{[4-(4-chlorophenyl)-5-(pyridin-4-yl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetohydrazide (CAS 893727-15-6)
- 3-(2-Chlorophenyl)-4-((2-hydroxy-3-methoxybenzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478253-84-8)
- 3-(2-Chlorophenyl)-4-((4-hydroxy-3-methoxybenzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478254-19-2)
Recommended Standards
- 5,6-Diamino-2-(chloromethyl)-8-morpholino-1,2-dihydrofuro[2,3-c][2,7]naphthyridine-9-carbonitrile (CAS 744230-48-6)
- 8-(2-(2-Chlorobenzylidene)hydrazinyl)-3-methyl-7-propyl-3,7-dihydro-1H-purine-2,6-dione (CAS 303969-62-2)
- 8-(2-(2-Chlorobenzylidene)hydrazinyl)-7-ethyl-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione (CAS 374912-02-4)
- (E)-N-{7-[1-(4-chloro-2-methylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-N'-methoxymethanimidamide (CAS 477865-59-1)
- 2-ethyl-2-methyl-oxetan-3-amine (CAS 2306275-67-0)
- Methyl 3-(3-fluorophenyl)-3-(2-(4-(4-fluorophenyl)piperazin-1-yl)acetamido)propanoate (CAS 860650-15-3)
- N-(4-fluorophenyl)-2-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazole-4-carboxamide (CAS 956753-84-7)
- Picloram (CAS 1918-02-1)
- Metoclopramide Impurity 114 (CAS CATO-C4X-1415114)
- (R)-2-(4-Fluorophenyl)-2-hydroxyacetic Acid (CAS 32222-45-0)
- 2-(Azepan-1-yl)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde (CAS 307326-40-5)
- 6-[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]hex-5-ynal (CAS 2504915-10-8)
- Norfloxacin Impurity 60 (CAS CATO-C4X-146860)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com