Pazopanib Impurity 24 CAS 444731-74-2
| CAS No. | 444731-74-2 |
| Molecular Formula | C13H12ClN5 |
| Molecular Weight | 273.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Pazopanib Impurity 24 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Pazopanib Impurity 24 (CAS 444731-74-2) is a certified pharmaceutical impurity reference standard with the molecular formula C13H12ClN5 and a molecular weight of 273.72 g/mol.
Pazopanib Impurity 24 (C13H12ClN5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Pazopanib Impurity 24 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H12ClN5 |
| Molecular Weight | 273.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Pazopanib Standards
- Pazopanib Impurity 5 (CAS 1226499-97-3)
- Pazopanib Impurity 63 (CAS 2369664-23-1)
- Pazopanib Impurity 13 (CAS CATO-C4X-172513)
- Pazopanib Impurity 47 (CAS 1821666-71-0)
- Pazopanib Impurity 8 (CAS 1296888-47-5)
- Pazopanib Impurity (CAS 1252927-45-9)
- Pazopanib USP Related Compound A (CAS 444731-75-3)
- Pazopanib Impurity 57 (CAS 444731-66-2)
Recommended Standards
- Alprazolam Impurity 4 (CAS 27610-14-6)
- Sunitinib Impurity 89 (CAS CATO-C4X-133389)
- tert-Butyl 3-(5-(chloromethyl)-1,2,4-oxadiazol-3-yl)azetidine-1-carboxylate (CAS 2138103-92-9)
- Clofenamide-d3 (CAS 1794816-92-4)
- Avibactam Impurity 22 (CAS 1174020-25-7)
- Famotidine Impurity 38 (CAS 24423-98-1)
- Cefoperazone Impurity 14 (CAS CATO-C4X-114914)
- Ciclesonide Impurity 17 (CAS CATO-C4X-320117)
- 2-Amino-6-bromoquinoline hydrochloride (CAS 1170935-81-5)
- Epiequisetin (CAS 255377-45-8)
- {5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}methanol (CAS 1638760-51-6)
- 4-(Acetoacetylamino)benzenesulfonic acid sodium salt (CAS 63503-98-0)
- 2-(2-propan-2-yloxyethoxy)ethanol (CAS 5412-01-1)
- Des-[Gly]31-Semaglutide(x TFA Salt) (CAS 873874-39-6(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com