Alprazolam Impurity 4 CAS 27610-14-6
| CAS No. | 27610-14-6 |
| Molecular Formula | C14H12ClN3O |
| Molecular Weight | 273.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Alprazolam Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Alprazolam Impurity 4 (CAS 27610-14-6, C14H12ClN3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Alprazolam Impurity 4 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 273.72 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H12ClN3O |
| Molecular Weight | 273.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Alprazolam Standards
- Alprazolam Impurity 5 (CAS 5220-83-7)
- Alprazolam Impurity 7 (CAS 1346606-48-1)
- Alprazolam Impurity 15 (CAS 963-39-3)
- Alprazolam EP Impurity A (CAS 27537-87-7)
- Alprazolam EP Impurity C (CAS 36916-19-5)
- Alprazolam Impurity 2 (CAS 4016-85-7)
- Alprazolam impurity 24 (CAS CATO-C4X-146024)
- Alprazolam impurity 25 (CAS CATO-C4X-146025)
Recommended Standards
- Sunitinib Impurity 89 (CAS CATO-C4X-133389)
- Pazopanib Impurity 24 (CAS 444731-74-2)
- tert-Butyl 3-(5-(chloromethyl)-1,2,4-oxadiazol-3-yl)azetidine-1-carboxylate (CAS 2138103-92-9)
- Pazopanib Impurity 5 (CAS 1226499-97-3)
- Febuxostat Impurity 48 (CAS 144060-52-6)
- Cyclophosphamide EP Impurity F (CAS 1071-28-9)
- Enarodustat Impurity 5 (CAS CATO-C4X-32285)
- Dopexamine dihydrochloride CRS (CAS 86484-91-5)
- tert-Butyl 3-cyano-3-methylpyrrolidine-1-carboxylate (CAS 1228537-69-6)
- Dibenzo-18-crown-6 (CAS 14187-32-7)
- 2-(4-Methoxyphenyl)imidazo[1,2-a]pyrimidine (CAS 31555-35-8)
- 1-[1,1-Dimethylethoxy) carbonyl] - 4-piperidinepropanoic Acid Methyl Ester (CAS 162504-75-8)
- 4-Hydroxybenzofuran-2-carbonitrile (CAS 53020-40-9)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com