Roxatidine Impurity 47 CAS 4530-46-5
| CAS No. | 4530-46-5 |
| Molecular Formula | C9H7Cl3O2 |
| Molecular Weight | 253.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Roxatidine Impurity 47 (C9H7Cl3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 253.51 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Roxatidine Impurity 47 (CAS 4530-46-5) is a certified pharmaceutical impurity reference standard with the molecular formula C9H7Cl3O2 and a molecular weight of 253.51 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Roxatidine Impurity 47 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7Cl3O2 |
| Molecular Weight | 253.51 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Related Roxatidine Standards
- Roxatidine Impurity N1 (CAS 73278-98-5)
- Roxatidine Impurity 58 (CAS 115062-97-0)
- Roxatidine Impurity 17 (CAS CATO-C4X-121317)
- Roxatidine Impurity 24 (CAS CATO-C4X-121324)
- Roxatidine Impurity 42 (CAS CATO-C4X-121342)
- Roxatidine Impurity 14 (CAS CATO-C4X-121314)
- Roxatidine Impurity 61 (CAS 83948-53-2)
- Roxatidine Impurity 83 (CAS CATO-C4X-121383)
Recommended Standards
- 58048-37-6 2-(2,4-Dichlorophenoxy)propanoyl chloride DTXSID20558730 (CAS 58048-37-6)
- Dotinurad Impurity 164 (CAS CATO-C4X-2494164)
- Methyl 2-chloro-2-(2,4-dichlorophenyl)acetate (CAS 225225-69-4)
- 5-bromo-4-chloro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one (CAS 1190316-24-5)
- Cefamandole Impurity 9 (CAS CATO-C4X-12219)
- Dapoxetine Impurity 59 HCl (CAS CATO-C4X-143959)
- Losartan Impurity 15 (CAS 114772-55-3)
- 5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 683229-62-1)
- N-(4-methoxyphenyl)-4-(pyrimidin-2-yloxy)benzamide (CAS 860789-51-1)
- (S)-tert-Butyl 3-cyclopropaneamidopiperidine-1-carboxylate (CAS 1286209-09-3)
- Dicyclohexylamine N6-((benzyloxy)carbonyl)-N2-(tert-butoxycarbonyl)-D-lysinate (CAS 76477-42-4)
- tert-Butyl (2-(3-(3-chlorophenyl)-10-oxopyrazolo[4,3-d]pyrido[1,2-a]pyrimidin-1(10H)-yl)ethyl)carbamate (CAS 1956321-40-6)
- Ethyl 1-[2-(methylamino)acetyl]piperidine-4-carboxylate (CAS 393155-08-3)
- Neuroendocrine Regulatory Peptide-1 (rat) (CAS 954420-51-0)
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